| 释义 |
- Receptor ligands α1-adrenergic receptor ligands Agonists Antagonists α2-adrenergic receptor ligands Agonists Antagonists β-adrenergic receptor ligands Agonists Antagonists
- Reuptake inhibitors Norepinephrine transporter (NET) inhibitors Vesicular monoamine transporter (VMAT) inhibitors
- Releasing agents
- Enzyme inhibitors Anabolism Phenylalanine hydroxylase (PAH) inhibitors Tyrosine hydroxylase inhibitors Aromatic L-amino acid decarboxylase (AAAD) inhibitors Dopamine-beta-hydroxylase (DBH) inhibitors Phenylethanolamine N-methyltransferase (PNMT) inhibitors Catabolism Monoamine oxidase (MAO) inhibitors Catechol-O-methyl transferase (COMT) inhibitors
- Others Precursors Cofactors Activity enhancers Release blockers Toxins
- References
{{Orphan|date=May 2017}}This is a list of adrenergic drugs. These are pharmaceutical drugs, naturally occurring compounds and other chemicals that influence the function of the neurotransmitter epinephrine (adrenaline). Receptor ligands α1-adrenergic receptor ligands Agonists {{flatlist|- Amidephrine
- Anisodamine
- Anisodine
- Cirazoline
- Dipivefrine
- Dopamine
- Ephedrine
- Epinephrine (adrenaline)
- Etilefrine
- Ethylnorepinephrine
- 5-Fluoronorepinephrine
- 6-Fluoronorepinephrine
- Indanidine
- Levonordefrin
- Metaraminol
- Methoxamine
- Methyldopa
- Midodrine
- Naphazoline
- Norepinephrine (noradrenaline)
- Octopamine
- Oxymetazoline
- Phenylephrine
- Phenylpropanolamine
- Pseudoephedrine
- Synephrine
- Tetrahydrozoline
}} Antagonists {{flatlist|- Abanoquil
- Adimolol
- Ajmalicine
- Alfuzosin
- Amosulalol
- Arotinolol
- Atiprosin
- Benoxathian
- Buflomedil
- Bunazosin
- Carvedilol
- CI-926
- Corynanthine
- Dapiprazole
- DL-017
- Domesticine
- Doxazosin
- Eugenodilol
- Fenspiride
- GYKI-12,743
- GYKI-16,084
- Indoramin
- Ketanserin
- L-765,314
- Labetalol
- Mephendioxan
- Metazosin
- Monatepil
- Moxisylyte (thymoxamine)
- Naftopidil
- Nantenine
- Neldazosin
- Nicergoline
- Niguldipine
- Pelanserin
- Phendioxan
- Phenoxybenzamine
- Phentolamine
- Piperoxan
- Prazosin
- Quinazosin
- Ritanserin
- RS-97,078
- SGB-1,534
- Silodosin
- SL-89.0591
- Spiperone
- Talipexole
- Tamsulosin
- Terazosin
- Tibalosin
- Tiodazosin
- Tipentosin
- Tolazoline
- Trimazosin
- Upidosin
- Urapidil
- Zolertine
}}Many tricyclic antidepressants, tetracyclic antidepressants, antipsychotics, ergolines, and some piperazines like buspirone, trazodone, nefazodone, etoperidone, and mepiprazole antagonize α1-adrenergic receptors as well, which contributes to their side effects such as orthostatic hypotension. α2-adrenergic receptor ligands Agonists {{flatlist|- Amitraz
- Apraclonidine
- Brimonidine
- Cannabivarin
- Clonidine
- Detomidine
- Dexmedetomidine
- Dihydroergotamine
- Dipivefrine
- Dopamine
- Ephedrine
- Ergotamine
- Epinephrine (adrenaline)
- Esproquin
- Etilefrine
- Ethylnorepinephrine
- 6-Fluoronorepinephrine
- Guanabenz
- Guanfacine
- Guanoxabenz
- Levonordefrin
- Lofexidine
- Medetomidine
- Methyldopa
- Mivazerol
- Naphazoline
- 4-NEMD
- (R)-3-Nitrobiphenyline
- Norepinephrine (noradrenaline)
- Phenylpropanolamine
- Piperoxan
- Pseudoephedrine
- Rilmenidine
- Romifidine
- Talipexole
- Tetrahydrozoline
- Tizanidine
- Tolonidine
- Urapidil
- Xylazine
- Xylometazoline
}} Antagonists {{flatlist|- Adimolol
- Aptazapine
- Atipamezole
- BRL-44408
- Buflomedil
- Cirazoline
- Efaroxan
- Esmirtazapine
- Fenmetozole
- Fluparoxan
- GYKI-12,743
- GYKI-16,084
- Idazoxan
- Mianserin
- Mirtazapine
- MK-912
- NAN-190
- Olanzapine
- Phentolamine
- Phenoxybenzamine
- Piperoxan
- Piribedil
- Pyrimidinylpiperazine
- Rauwolscine
- Rotigotine
- SB-269,970
- Setiptiline
- Spiroxatrine
- Sunepitron
- Tolazoline
- Yohimbine
}}Many atypical antipsychotics and azapirones like buspirone and gepirone (via metabolite pyrimidinylpiperazine) antagonize α2-adrenergic receptors as well. β-adrenergic receptor ligands Agonists {{flatlist|- Abediterol
- Amibegron
- Arbutamine
- Arformoterol
- Arotinolol
- Bambuterol
- Befunolol
- Bitolterol
- Bromoacetylalprenololmenthane (BAAM)
- Broxaterol
- Buphenine
- Carbuterol
- Cimaterol
- Clenbuterol
- Denopamine
- Deterenol
- Dipivefrine
- Dobutamine
- Dopamine
- Dopexamine
- Ephedrine
- Epinephrine (adrenaline)
- Etafedrine
- Etilefrine
- Ethylnorepinephrine
- Fenoterol
- 2-Fluoronorepinephrine
- 5-Fluoronorepinephrine
- Formoterol
- Hexoprenaline
- Higenamine
- Indacaterol
- Isoetarine
- Isoprenaline (isoproterenol)
- N-Isopropyloctopamine
- Isoxsuprine
- Labetalol
- Levonordefrin
- Levosalbutamol
- Mabuterol
- Methoxyphenamine
- Methyldopa
- Norepinephrine (noradrenaline)
- Orciprenaline
- Oxyfedrine
- Phenylpropanolamine
- Pirbuterol
- Prenalterol
- Ractopamine
- Procaterol
- Pseudoephedrine
- Quinterenol
- Reproterol
- Rimiterol
- Ritodrine
- Salbutamol (albuterol)
- Salmeterol
- Solabegron
- Terbutaline
- Tretoquinol
- Tulobuterol
- Xamoterol
- Zilpaterol
- Zinterol
}} Antagonists {{flatlist|- Acebutolol
- Adaprolol
- Adimolol
- Afurolol
- Alprenolol
- Alprenoxime
- Amosulalol
- Ancarolol
- Arnolol
- Arotinolol
- Atenolol
- Befunolol
- Betaxolol
- Bevantolol
- Bisoprolol
- Bopindolol
- Bornaprolol
- Brefonalol
- Bucindolol
- Bucumolol
- Bufetolol
- Bufuralol
- Bunitrolol
- Bunolol
- Bupranolol
- Butaxamine
- Butidrine
- Butofilolol
- Capsinolol
- Carazolol
- Carpindolol
- Carteolol
- Carvedilol
- Celiprolol
- Cetamolol
- Cicloprolol
- Cinamolol
- Cloranolol
- Cyanopindolol
- Dalbraminol
- Dexpropranolol
- Diacetolol
- Dichloroisoprenaline
- Dihydroalprenolol
- Dilevalol
- Diprafenone
- Draquinolol
- Ecastolol
- Epanolol
- Ericolol
- Ersentilide
- Esatenolol
- Esmolol
- Eugenodilol
- Exaprolol
- Falintolol
- Flestolol
- Flusoxolol
- Hydroxycarteolol
- Hydroxytertatolol
- ICI-118,551
- Idropranolol
- Indenolol
- Indopanolol
- Iodocyanopindolol
- Iprocrolol
- Isoxaprolol
- Isamoltane
- Labetalol
- Landiolol
- Levobetaxolol
- Levobunolol
- Levocicloprolol
- Levomoprolol
- Medroxalol
- Mepindolol
- Metalol
- Metipranolol
- Metoprolol
- Moprolol
- Nadolol
- Nadoxolol
- Nafetolol
- Nebivolol
- Neraminol
- Nifenalol
- Nipradilol
- Oberadilol
- Oxprenolol
- Pacrinolol
- Pafenolol
- Pamatolol
- Pargolol
- Parodilol
- Penbutolol
- Penirolol
- PhQA-33
- Pindolol
- Pirepolol
- Practolol
- Primidolol
- Procinolol
- Pronethalol
- Propafenone
- Propranolol
- Ridazolol
- Ronactolol
- Soquinolol
- Sotalol
- Spirendolol
- SR 59230A
- Sulfinalol
- TA-2005
- Talinolol
- Tazolol
- Teoprolol
- Tertatolol
- Tienoxolol
- Tilisolol
- Timolol
- Tiprenolol
- Tolamolol
- Toliprolol
- Tribendilol
- Trigevolol
- Xibenolol
- Xipranolol
}} Reuptake inhibitors Norepinephrine transporter (NET) inhibitors {{flatlist|- {{nobold|Selective norepinephrine reuptake inhibitors}}
Amedalin Atomoxetine (tomoxetine) Ciclazindol Daledalin Esreboxetine Lortalamine Mazindol Nisoxetine Reboxetine Talopram Talsupram Tandamine Viloxazine - {{nobold|Norepinephrine-dopamine reuptake inhibitors}}
Amineptine Bupropion (amfebutamone) Fencamine Fencamfamine Lefetamine Levophacetoperane LR-5182 Manifaxine Methylphenidate Nomifensine O-2172 Radafaxine - {{nobold|Serotonin-norepinephrine reuptake inhibitors}}
Bicifadine Desvenlafaxine Duloxetine Eclanamine Levomilnacipran Milnacipran Sibutramine Venlafaxine - {{nobold|Serotonin-norepinephrine-dopamine reuptake inhibitors}}
Brasofensine Diclofensine DOV-102,677 DOV-21,947 DOV-216,303 JNJ-7925476 JZ-IV-10 Methylnaphthidate Naphyrone NS-2359 PRC200-SS SEP-225,289 SEP-227,162 Tesofensine - {{nobold|Tricyclic antidepressants}}
Amitriptyline Butriptyline Cianopramine Clomipramine Desipramine Dosulepin Doxepin Imipramine Lofepramine melitracen Nortriptyline Protriptyline Trimipramine - {{nobold|Tetracyclic antidepressants}}
Amoxapine Maprotiline Mianserin Oxaprotiline Setiptiline - {{nobold|Others}}
Cocaine CP-39,332 EXP-561 Fezolamine Ginkgo biloba Indeloxazine Nefazodone Nefopam Pridefrine Tapentadol Teniloxazine Tramadol Ziprasidone
}} Vesicular monoamine transporter (VMAT) inhibitors {{flatlist|- Ibogaine
- Reserpine
- Tetrabenazine
- Bietaserpine
}} Releasing agents {{flatlist|- {{nobold|Morpholines}}
Fenbutrazate Morazone Phendimetrazine Phenmetrazine - {{nobold|Oxazolines}}
Aminorex Clominorex Cyclazodone Fenozolone Fluminorex 4-Methylaminorex Pemoline Thozalinone - {{nobold|Phenethylamines (also amphetamines, cathinones, phentermines, etc.)}}
2-OH-PEA 4-CAB 4-FA 4-FMA 4-MA 4-MMA Alfetamine Amfecloral Amfepentorex Amfepramone Amphetamine - dextroamphetamine
- levoamphetamine
Amphetaminil β-Me-PEA BDB Benzphetamine BOH Buphedrone Butylone Cathine Cathinone Clobenzorex Clortermine D-Deprenyl Dimethylamphetamine Dimethylcathinone (dimethylpropion, metamfepramone) DMA DMMA EBDB Ephedrine Ethcathinone Ethylamphetamine Ethylone Famprofazone Fenethylline Fenproporex Flephedrone Fludorex Furfenorex Hordenine IAP IMP Lisdexamfetamine Lophophine MBDB MDA (tenamfetamine) MDEA MDMA MDMPEA MDOH MDPEA Mefenorex Mephedrone Mephentermine Methamphetamine - dextromethamphetamine
- levomethamphetamine
Methcathinone Methedrone Methylone NAP Ortetamine Paredrine pBA pCA Pentorex (phenpentermine) Phenethylamine Pholedrine Phenpromethamine Phentermine Phenylpropanolamine pIA Prenylamine Propylamphetamine Pseudoephedrine Selegiline (L-deprenyl) Tiflorex Tyramine Xylopropamine Zylofuramine - {{nobold|Piperazines}}
Benzylpiperazine (BZP) 2,5-Dimethoxy-4-bromobenzylpiperazine (2C-B-BZP) Methylbenzylpiperazine (MBZP) Metachlorophenylpiperazine (mCPP) Methylenedioxybenzylpiperazine (MDBZP) Methoxyphenylpiperazine (MeOPP) Parafluorophenylpiperazine (pFPP) - {{nobold|Others}}
2-Amino-1,2-dihydronaphthalene 2-Aminoindane 2-Aminotetralin 2-Benzylpiperidine 4-Benzylpiperidine Clofenciclan Cyclopentamine Cypenamine Cyprodenate Feprosidnine Gilutensin Heptaminol Hexacyclonate Indanorex 5-Iodo-2-aminoindane (5-IAI) Isometheptene Methylhexanamine Octodrine Phthalimidopropiophenone Propylhexedrine Tuaminoheptane
}} Enzyme inhibitors Anabolism Phenylalanine hydroxylase (PAH) inhibitors {{flatlist|
}} Tyrosine hydroxylase inhibitors {{flatlist|- 3-Iodotyrosine
- Aquayamycin
- Bulbocapnine
- Metirosine
- Oudenone
}} Aromatic L-amino acid decarboxylase (AAAD) inhibitors {{flatlist|- Benserazide
- Carbidopa
- Genistein
- Methyldopa
}} Dopamine-beta-hydroxylase (DBH) inhibitors {{flatlist|- Bupicomide
- Disulfiram
- Dopastin
- Fusaric acid
- Nepicastat
- Phenopicolinic acid
- Tropolone
}} Phenylethanolamine N-methyltransferase (PNMT) inhibitors {{flatlist|- CGS-19281A
- SKF-64139
- SKF-7698
}} Catabolism Monoamine oxidase (MAO) inhibitors {{flatlist|- {{nobold|Nonselective}}
Benmoxin Caroxazone Echinopsidine Furazolidone Hydralazine Indantadol Iproclozide Iproniazid Isocarboxazid Isoniazid Linezolid Mebanazine Metfendrazine Nialamide Octamoxin Paraxazone Phenelzine Pheniprazine Phenoxypropazine Pivalylbenzhydrazine Procarbazine Safrazine Tranylcypromine - {{nobold|MAO-A selective}}
Amiflamine Bazinaprine Befloxatone Befol Brofaromine Cimoxatone Clorgiline Esuprone Harmala alkaloids - harmine
- harmaline
- tetrahydroharmine
- harman
- norharman
- etc.
Methylene Blue Metralindole Minaprine Moclobemide Pirlindole Sercloremine Tetrindole Toloxatone Tyrima - {{nobold|MAO-B selective}}
D-Deprenyl Selegiline (L-deprenyl) Ladostigil Lazabemide Milacemide Mofegiline Pargyline Rasagiline Safinamide
}}MAO-B inhibitors also influence norepinephrine/epinephrine levels since they inhibit the breakdown of their precursor dopamine. Catechol-O-methyl transferase (COMT) inhibitors {{flatlist|
}} Others Precursors {{flatlist|- L-Phenylalanine → L-tyrosine → L-DOPA (levodopa) → dopamine
- L-DOPS (droxidopa)
}} Cofactors {{flatlist|- Ferrous iron (Fe2+)
- S-Adenosyl-L-methionine
- Vitamin B3
- niacin
- nicotinamide → NADPH
- Vitamin B6 (pyridoxine, pyridoxamine, pyridoxal → Pyridoxal phosphate)
- Vitamin B9 (folic acid → tetrahydrofolic acid)
- Vitamin C
- Zinc (Zn2+)
}} Activity enhancers {{flatlist|- Benzofuranylpropylaminopentane (BPAP)
- Phenylpropylaminopentane (PPAP)
}} Release blockers {{flatlist|- Bethanidine
- Bretylium
- Guanadrel
- Guanazodine
- Guanclofine
- Guanethidine
- Guanoxan
}} Toxins {{flatlist|- Oxidopamine (6-hydroxydopamine)
}}References{{Unreferenced|date=October 2011}}{{Adrenergics}}{{Monoamine reuptake and release modulators}}{{Monoamine metabolism modulators}}{{Monoamine neurotoxins}} 1 : Alpha-adrenergic agonists |