This is a list of LGBT rights organizations in the United States. It does not include LGBT organizations affiliated with political parties.
| Organization | Year founded | Focus | Status | | Accord Alliance | 2008 | Healthcare | {{site active}} |
| ACT UP | 1987 | HIV/AIDS | {{site active}} |
| Advocates for Informed Choice | 2006 | Intersex | Renamed Interact}} |
| LGBT Mormons, Families & Friends | 1977 | Mormons | {{site active}} |
| Against Equality | 2009 | Anti-capitalist discourse |
| American Foundation for Equal Rights | 2009 | Prop. 8 opposition | {{site active}} |
| American Veterans for Equal Rights | 1990 | Veterans | {{site active}} |
| Athlete Ally | 2011 | Sports | {{site active}} |
| Atticus Circle | 2004 | Straight allies | {{site active}} |
| Bash Back! | 2007 | Anarchist direct action | Dissolved}} |
| Bialogue | 2005 | Bisexuality |
| BiNet USA | 1990 | Bisexuality | {{site active}} |
| Bisexual Resource Center | 1985 | Bisexuality | {{site active}} |
| Campus Pride | 2001 | Students | {{site active}} |
| Cheer, Dorothy, Cheer! | 2002 | Awareness |
| Children of Lesbians and Gays Everywhere (COLAGE) | 1990 | Children of LGBTQ parents | {{site active}} |
| Consortium of Higher Education LGBT Resource Professionals | | {{small>(1997)}} LGBT student centers | {{site active}} |
| Daughters of Bilitis | 1955 | Lesbian | Dissolved}} |
| El/La Para TransLatinas | 2006 | Latina trans women | {{site active}} |
| Empowering Spirits Foundation | 2008 | Community service | Dissolved}} |
| Equality Across America | 2009 | National Equality March | Dissolved}} |
| Equality Federation | 1997 | {{site active}} |
| Family Equality Council | 1979 |
| Fight OUT Loud | 2007 |
| Fine By Me | 2003 | Merged into {{nowrap|Atticus Circle}}}} |
| Freedom to Marry | 2003 | Marriage equality | Dissolved}} |
| GLBTQ Legal Advocates & Defenders (GLAD) | 1978 |
| Gay and Lesbian Medical Association (GLMA) | | {{small>(1981)}} Homophobia in medicine | {{site active}} |
| Gay & Lesbian Victory Fund | 1991 |
| Gay, Lesbian and Straight Education Network (GLSEN) | 1990 |
| Gay Liberation Front#GLF in the United States (GLF) | 1969 | Dissolved}} |
| Gay Rights National Lobby | 1976 | Merged into the HRC}} |
| Gays Against Guns | Gun control | {{site active}} |
| GenderPAC (GPAC) | 1995 | Dissolved}} |
| GetEQUAL | 2010 | {{site active}} |
| GLAAD | 1985 | {{site active}} |
| GLIFAA | 1992 | {{site active}} |
| Global Equality Fund | 2011 |
| GSA Network | 1998 | {{site active}} |
| Human Rights Campaign (HRC) | 1980 | {{site active}} |
| Immigration Equality | 1994 | {{site active}} |
| interACT | 2006 | {{site active}} |
| Integrity USA | 1974 |
| International Foundation for Gender Education (IFGE) | 1987 |
| Intersex Campaign for Equality (IC4E) formerly OII-USA | 2011 |
| Join the Impact | 2008 |
| Keshet | 2001 | {{site active}} |
| LPAC | 2012 | {{site active}} |
| Lambda Legal | 1971 | {{site active}} |
| Lavender Menace | 1970 |
| Lesbian Avengers | 1992 |
| Love Makes a Family | 1992 | Dissolved}} |
| Marriage Equality USA | 1998 |
| Mattachine Society | 1950 |
| Matthew Shepard Foundation | 1998 | {{site active}} |
| National Black Justice Coalition (NBJC) | 2003 | {{site active}} |
| National Center for Lesbian Rights (NCLR) | 1977 | {{site active}} |
| National Center for Transgender Equality (NCTE) | 2003 | {{site active}} |
| National Coalition of Black Lesbians and Gays | 1978 | Dissolved}} |
| National LGBT Chamber of Commerce (NGLCC) | 2002 | {{site active}} |
| National Lesbian and Gay Journalists Association (NLGJA) | 1990 | {{site active}} |
| National LGBTQ Task Force (The Task Force) | 1973 | {{site active}} |
| National Transgender Advocacy Coalition | 1999 |
| National Youth Advocacy Coalition (NYAC) | 1993 | Dissolved in 2011}} |
| NOH8 Campaign | 2009 | Prop. 8 |
| North American Conference of Homophile Organizations (NACHO) | 1966 | Dissolved in 1970}} |
| ONE National Gay & Lesbian Archives | 1952 |
| Out & Equal | 1996 | {{site active}} |
| OutServe-SLDN | 2012 | {{site active}} |
| PFLAG | 1973 | {{site active}} |
| Pride at Work | 1994 | {{site active}} |
| Queer Nation | 1990 |
| RESYST | 2000 | Dissolved}} |
| Rainbow Sash | 1998 |
| Services & Advocacy for GLBT Elders (SAGE) | 1979 | {{site active}} |
| Servicemembers Legal Defense Network (SLDN) | 1993 | Merged into OutServe-SLDN}} |
| Society for Human Rights | 1924 | Dissolved}} |
| Soulforce | 1998 |
| StartOut | 2009 | {{site active}} |
| Sylvia Rivera Law Project | 2002 | Legal aid | {{site active}} |
| Think Again | 1997 | Dissolved}} |
| Trans Student Educational Resources | 2011 | {{site active}} |
| Transgender Law Center | 2002 | {{site active}} |
| Truth Wins Out | 2006 | Dissolved}} |