This is a partial list of Non-governmental organization (NGOs) based in Karachi, Sindh, Pakistan.
| Name of NGO | Cause |
|---|
| Aahung | Aahung is a Karachi-based non-governmental organisation which aims to improve the sexual and reproductive health of men, women, and adolescents across Pakistan |
| Chhipa Welfare Association | Chhipa Ambulances provides free paramedic services to common people |
| Darul Sukun | A home for children and adults with deformity or mentally challenged. |
| Edhi Foundation | A non-profit social welfare program in Pakistan, founded by Abdul Sattar Edhi |
| Family Educational Services Foundation | The Deaf Reach Program was established in Pakistan in 1998, initially working informally with deaf youth and young adults. |
| Gul Bahao | Provides practical solutions for low cost housing, water sanitation and garbage disposal. |
| Idara-e-Amn-o-Insaf | The charity deals with social and labor issues. |
| JDC Welfare Organization | A non-profit Charitable Organization in Pakistan |
| Layton Rahmatulla Benevolent Trust | LRBT provides aid preventing the suffering caused by blindness and other eye elements |
| Mahvash & Jahangir Siddiqui Foundation | Provides healthcare, education and social enterprise through sustainable development to underprivileged. |
| Marie Adelaide Leprosy Centre | The charity provides full-service leprosy treatment and rehabilitation center, free to patients. |
| RAST Foundation | The non-profit organisation provides teachers training and certification for Early Childhood Education (ECE) and higher classes |
| Saylani Welfare International Trust | A non-profit social welfare program in Pakistan, founded by Maulana Bashir Farooq Qadri |
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