Pennsylvania has a number of professional and semi-professional sports teams in various sports and leagues.
| Philadelphia Ramblers | Sport | EHL |
|---|
| Lehigh Valley IronPigs | Baseball | International League |
| Scranton/Wilkes-Barre RailRiders | Baseball | International League |
| Altoona Curve | Baseball | Eastern League |
| Erie SeaWolves | Baseball | Eastern League |
| Harrisburg Senators | Eastern League |
| Reading Fightin Phils | Eastern League |
| State College Spikes | New York–Penn League |
| Williamsport Crosscutters | Baseball | New York–Penn League |
| Lancaster Barnstormers | Baseball | Atlantic League of Professional Baseball |
| York Revolution | Baseball | Atlantic League of Professional Baseball |
| Washington Wild Things | Baseball | Frontier League |
| Philadelphia Destroyers | Basketball | American Professional Basketball League |
| Harrisburg Horizon | Basketball | Eastern Basketball Alliance |
| York Mad Ants | Basketball | Eastern Basketball Alliance |
| Lehigh Valley Steelhawks | Football | National Arena League |
| Philadelphia Soul | Football | Arena Football League |
| Hershey Bears | Ice hockey | American Hockey League |
| Lehigh Valley Phantoms | Ice hockey | American Hockey League |
| Wilkes-Barre/Scranton Penguins | Ice hockey | American Hockey League |
| Reading Royals | Ice hockey | ECHL |
| Bucks County Sharks | Rugby league | USA Rugby League |
| Philadelphia Fight | Rugby league | USA Rugby League |
| Pittsburgh Sledgehammers | Rugby league | USA Rugby League |
| Bethlehem Steel FC | Soccer | United Soccer League |
| Penn FC | Soccer | United Soccer League |
| Pittsburgh Riverhounds SC | Soccer | United Soccer League |
| Buxmont Torch FC | Soccer | National Premier Soccer League |
| Erie Commodores FC | Soccer | National Premier Soccer League |
| Electric City Shock SC | Soccer | National Premier Soccer League |
| Hershey FC | Soccer | National Premier Soccer League |
| Junior Lone Star FC | Soccer | National Premier Soccer League |
| Lehigh Valley United Sonic | Soccer | Premier Development League |
| Pittsburgh Riverhounds U23 | Soccer | Premier Development League |
| Reading United A.C. | Soccer | Premier Development League |