Little Mother may refer to:

• Little Mother (1929 film), a 1929 Our Gang short silent comedy film directed by Robert F. McGowan
• Little Mother (1935 film), a 1935 Austrian-Hungarian comedy film directed by Henry Koster
• Little Mother (1973 film), a 1973 drama, romance, cult film directed by Radley Metzger

• Anguilla amboinensis
• Anguilla ancestralis
• Anguilla arracana
• Anguilla at the 2011 World Championships in Athletics
• Anguilla at the 2013 World Championships in Athletics
• Anguilla at the 2014 Commonwealth Games
• Anguilla australis australis
• Anguilla australis schmidti
• Anguilla Bank Ameiva
• Anguilla bank anole
• Anguilla Bank Anole
• Anguilla Bank skink
• Anguilla Bank Skink Lizard
• Anguilla bleekeri
• Anguilla borneensis
• Anguilla Branch of The Scout Association
• Anguilla breviceps
• Anguilla brevirostris
• Anguilla cantori
• Anguilla capensis
• Anguilla celebensis
• Anguilla celebesensis
• Anguilla cellebesensis
• Anguilla company law
• Anguilla (constellation)