LSG-1 or LSG1 may refer to:

• Farrar LSG-1 Bird Flight Machine, research glider
• LSG1, a human enzyme

• Once Upon a Dream (Sleeping Beauty)
• Once Upon a Dream (Sleeping Beauty song)
• Once Upon a Dream (song)
• Once Upon a Dream (TV series)
• Once Upon a Future King
• Once Upon a Kiss
• Once Upon a Love
• Once Upon a Mattress (2005 film)
• Once Upon a Mirage
• Once Upon a Monster
• Once Upon a Nightwish: The Official Biography 1996 – 2006
• Once Upon Another Time
• Once Upon Another Time (film)
• Once Upon a Scoundrel
• Once Upon a Secret
• Once Upon A Shattered Life
• Once Upon a Song
• Once Upon a Summertime
• Once Upon a Thursday
• Once Upon a Time (1918 film)
• Once Upon a Time (1976 film)
• Once Upon a Time (2013 film)
• Once upon a Time (2013 film)
• Once upon a time abc
• Once Upon a Time: A Floating Opera