词条 | Manuel Morales |
释义 |
| name = Manuel Francisco Morales | image = | alt = | caption = | birth_date = {{Birth date|1919|07|23}} | birth_place = San Pedro, Sula, Honduras | death_date = {{Death date and age|2009|11|12|1919|07|23}} | death_place = | resting_place = | residence = | citizenship = USA | nationality = Honduran | fields = Biophysics, Cell biology | workplaces = University of Chicago, Naval Medical Research Institute, Dartmouth Medical School, UCSF, University of the Pacific | alma_mater = UC Berkeley A.B., Harvard University Ph.D | thesis_title = | thesis_url = | thesis_year = | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = energetics of ATP hydrolysis, myosin structure by FRET | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = National Academy of Sciences, Order of the Rising Sun | signature = | signature_alt = | website = | footnotes = | spouse = }} Manuel Francisco Morales (July 23, 1919 – November 12, 2009) was a Honduran-born American biophysicist who did pivotal research on the molecular basis of muscle contraction. Scientific careerIn the 1950s at the Naval Medical Research Institute, Morales and Terrell Hill showed that the high energy of the terminal phosphate bond in ATP was due to electrostatic repulsion between the three phosphate groups,[1][1] and he and Richard Podolsky measured the heat of hydrolysis for ATP cleavage, the fundamental energy currency of biological metabolism.[1][2] Awards and serviceMorales was elected a member of the US National Academy of Sciences and awarded the Order of the Rising Sun (Japan). He served as President of the Biophysical Society for 1968–69,[3] and was the founding editor of the Annual Review of Biophysics.[4] Key publications
References1. ^Hill TL, Morales MF. (1951) On "High Energy Phosphate Bonds" of Biochemical Interest. J Am Chem Soc 73: 1656–1660 ({{doi|10.1021/ja01148a072}}) {{authority control}}{{DEFAULTSORT:Morales, Manuel}}2. ^Podolsky RJ, Morales MF. (1956) The Enthalpy Change of Adenosine Triphosphate Hydrolysis J Biol Chem 218: 945–959 (pdf) 3. ^{{cite web |url=http://www.biophysics.org/AboutUs/Leadership/PastOfficers/tabid/2241/Default.aspx |title=List of past presidents, Biophysical Society}} 4. ^1 2 Biophysical Society: Newsletter: Obituary: Manuel Francisco Morales (accessed 11 February 2013) 7 : American biophysicists|Members of the United States National Academy of Sciences|1919 births|2009 deaths|Honduran emigrants to the United States|Harvard Medical School alumni|University of California, Berkeley alumni |
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