“María Blasco Marhuenda”的意思、由来-开放百科全书

María Antonia Blasco Marhuenda (born 1965), known as María Blasco, is a Spanish molecular biologist. She is the current director of the Spanish National Centre for Cancer Research (Centro Nacional de Investigaciones Oncológicas).

Life

Blasco was born in 1965. She obtained her PhD in 1993 for her research at the Centro de Biología Molecular Severo Ochoa (UAM-CSIC), under the supervision of Margarita Salas. That same year, Blasco joined the Cold Spring Harbor Laboratory in New York (USA) as a Postdoctoral Fellow under the leadership of Carol W. Greider (who was to win a Nobel Prize in 2009).

In 1997 she returned to Spain to start her own research at the Centro Nacional de Biotecnología in Madrid. She joined the Centro Nacional de Investigaciones Oncológicas (CNIO) in 2003 as Director of the Molecular Oncology Programme and Leader of the Telomeres and Telomerase Group. In 2005 she was also assigned as Vice-Director of Basic Research and in 2011 she was appointed as CNIO Director.^[1]^[2]

Research

Professional experience

Honours and awards

Publications

More than 200 articles, see MA Blasco at [https://scholar.google.es/scholar?q=MA+blasco&hl=en&as_sdt=0 Google Scholar]

References

1. ^{{cite web|title=Biosketch: María A. Blasco at CNIO|url=https://www.cnio.es/es/grupos/plantillas/curriculum.asp?pag=39|publisher=CNIO}}
2. ^La investigadora María Blasco sustituye a Barbacid al frente del CNIO, 22/6/2011 - El País
3. ^{{cite journal|last=Blasco|first=MA|author2=Funk W |author3=Villaponteau B |author4=Greider CW |title=Functional characterization and developmental regulation of mouse telomerase RNA component.|journal=Science|year=1995|volume=269|pages=1267–1270 |doi=10.1126/science.7544492}}
4. ^{{cite journal|last=Blasco|first=MA|author2=Lee H-W |author3=Hande P |author4=Samper E |author5=Lansdorp P |author6=DePinho R |author7=Greider CW |title=Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.|journal=Cell|year=1997|volume=91|pages=25–34 |doi=10.1016/s0092-8674(01)80006-4 |pmid=9335332}}
5. ^{{cite journal|last=Blasco|first=MA|author2=Garcia-Cao, M. |author3=O'Sullivan, R. |author4=Peters, A.H. |author5=Jenuwein, T. |title=Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases|journal=Nature Genetics|year=2004|volume=36|pages=94–99 |doi=10.1038/ng1278 |issue=1}}
6. ^{{cite journal|last=Schoeftner, S.|author2=Blasco, MA|title=Developmentally regulated transcription of mammalian telomeres by DNA dependent RNA polymerase II|journal=Nature Cell Biology|year=2008|volume=10|pages=228–236|doi=10.1038/ncb1685|pmid=18157120|issue=2}}
7. ^{{cite journal|last=Benetti, R.|author2=García-Cao, M. |author3=Blasco, MA |title=Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres|journal=Nature Genetics|year=2007|volume=39|pages=243–250|doi=10.1038/ng1952|issue=2|pmid=17237781}}
8. ^{{cite journal|last=Flores, I.|author2=Canela, A. |author3=Vera, E. |author4=Tejera, A. |author5=Cotsarelis, G. |author6=Blasco, MA |title=The longest telomeres: a general signature of adult stem cell compartments|journal=Genes & Development|year=2008|volume=22|pages=654–667 |doi=10.1101/gad.451008 |pmid=18283121 |pmc=2259034}}
9. ^{{cite journal|last=Tomas, A. |author2=Flores, I. |author3=Fernandez-Marcos, P. |author4=Cayuela, M.L |author5=Maraver, A. |author6=Tejera, A. |author7=Borras, C. |author8=Matheu, A. |author9=Klatt, P. |author10=Flores, J.M. |author11=Viña, J. |author12=Serrano, M. |author13=Blasco, MA|title=Telomerase reverse transcriptase delays aging in cancer resistant mice|journal=Cell|volume=135|pages=609–622|doi=10.1016/j.cell.2008.09.034|pmid=19013273|issue=4|date=November 2008}}
10. ^{{cite journal|last=arion, R.M.|author2=Strati, K. |author3=Li, H. |author4=Murga, M. |author5=Blanco, R. |author6=Ortega, S. |author7=Fernandez-Capetillo, O. |author8=Serrano, M. |author9=Blasco, MA |title=A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity.|journal=Nature|volume=460|pages=1149–1153 |doi=10.1038/nature08287 |pmid=19668189 |issue=7259 |date=August 2009 |pmc=3624089}}
11. ^{{cite journal|last=Martinez, P.|author2=Thanasoula, M. |author3=Muñoz, P. |author4=Liao, C. |author5=Tejera, A. |author6=McNees, C. |author7=Flores, J.M. |author8=Fernández-Capetillo, O. |author9=Tarsounas, M. |author10=Blasco, MA |title=Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice|journal=Genes Dev.|year=2009|volume=23|pages=2060–2075 |doi=10.1101/gad.543509 |pmid=19679647 |pmc=2751970}}
12. ^{{Cite journal | last1 = Blasco | first1 = M. A. A. | title = Mice with bad ends: Mouse models for the study of telomeres and telomerase in cancer and aging | doi = 10.1038/sj.emboj.7600598 | journal = The EMBO Journal | volume = 24 | issue = 6 | pages = 1095–1103 | year = 2005 | pmid = 15775986| pmc =556402 }}

External links

AXA Research Fund

Vall d’Hebron Institut de Recerca (VHIR)

[https://web.archive.org/web/20140521160956/http://www.cnie.es/ Spanish National Centre for Research on Ageing (CNIE)]

Lifeboat Foundation

[https://www.youtube.com/watch?v=vWkUeDEhRmU IDEAS 2011 Award in Innovation and Social Transformation]

[https://web.archive.org/web/20120511174143/http://embo.org/documents/embo_goldmedal04.pdf The 2004 winner of the EMBO Gold Medal is María Blasco]

Josef Steiner Cancer Research Award 2003.

FEBS Anniversary Prize

5 : 1965 births|Living people|Spanish biologists|Spanish women scientists|People from Alicante