词条 | MC21-A |
释义 |
| Name = | ImageFile = MC21-A.svg | ImageSize = 150px | ImageAlt = | ImageCaption = | IUPACName = 2,4-Dibromo-6-(3,5-dibromo-2-hydroxyphenyl)phenol | SystematicName = | OtherNames = Bromophene; 2,2'-Dihydroxy-3,3',5,5'-tetrabromobiphenyl; 3,3',5,5'-Tetrabromo-2,2'-biphenyldiol |Section1={{Chembox Identifiers | Abbreviations = | CASNo = 21987-62-2 | CASNo_Comment = | CASNo_Ref = | PubChem = 30891 | PubChem_Comment = | ChemSpiderID = 28660 | ChemSpiderID_Comment = | EINECS = | EC_number = | UNNumber = | DrugBank = | KEGG = | MeSHName = 3,3',5,5'-tetrabromo-2,2'-biphenyldiol | ChEBI = | RTECS = DV5185000 | SMILES = C1=C(C=C(C(=C1Br)O)C2=CC(=CC(=C2O)Br)Br)Br | InChI = 1S/C12H6Br4O2/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)18/h1-4,17-18H | InChIKey = TXODBIOSWNNKJM-UHFFFAOYSA-N | Beilstein = | Gmelin = | 3DMet = }} |Section2={{Chembox Properties | C=12 | H=6 | Br=4 | O=2 | Appearance = Cryst. (CHCl3) | Density = | MeltingPtC = 205 to 207 | MeltingPt_notes = | BoilingPt = | BoilingPt_notes = | LogP = | VaporPressure = | HenryConstant = | AtmosphericOHRateConstant = | pKa = | pKb = | Solubility = Sol. MeOH, CHCl3 insol. H2O, hexane | SolubleOther = | Solvent = }} |Section3={{Chembox Structure | CrystalStruct = | Coordination = | MolShape = }} |Section4={{Chembox Thermochemistry | DeltaHc = | DeltaHf = | Entropy = | HeatCapacity = }} |Section5={{Chembox Pharmacology | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = }} |Section6={{Chembox Explosive | ShockSens = | FrictionSens = | DetonationV = | REFactor = }} |Section7={{Chembox Hazards | ExternalSDS = | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = | SPhrases = | RSPhrases = | FlashPt = | AutoignitionPt = | ExploLimits = | LD50 = | PEL = }} |Section8={{Chembox Related | OtherAnions = | OtherCations = | OtherFunction = MC21-B Polybrominated biphenyl | OtherFunction_label = biphenyls | OtherCompounds = }}MC21-A (bromophene) is an bactericidal antibiotic isolated from the O-BC30 strain of a new marine bacterium, Pseudoalteromonas phenolica.[1] References1. ^{{cite journal |last1=Isnansetyo |first1=Alim |last2=Kamei |first2=Yuto |date=February 2003 |title=MC21-A, a Bactericidal Antibiotic Produced by a New Marine Bacterium, Pseudoalteromonas phenolica sp. nov. O-BC30T, against Methicillin-Resistant Staphylococcus aureus |journal=Antimicrobial Agents and Chemotherapy |location=Washington, DC |publisher=American Society for Microbiology |volume=47 |issue=2 |pages=480–488 |doi=10.1128/AAC.47.2.480-488.2003 |issn=1098-6596 |oclc=678833406 |pmc=151744 |pmid=12543647}} {{organohalide-stub}} 5 : Antibiotics|Bromoarenes|Phenols|Biphenyls|Halogen-containing natural products |
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