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词条 Methade
释义

  1. Chemical derivatives

  2. Related compounds

  3. References

{{Chembox
| ImageFile = Methade.svg
| ImageSize = 200px
| IUPACName = 6-(dimethylamino)-4,4-diphenylheptane
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo =
| PubChem =
| ChemSpiderID =
| SMILES = CN(C(CC(CCC)(C1=CC=CC=C1)C2=CC=CC=C2)C)C
| StdInChI = 1S/C21H29N/c1-5-16-21(17-18(2)22(3)4,19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-15,18H,5,16-17H2,1-4H3
| StdInChIKey = MCFVCWVAZLRHPN-UHFFFAOYSA-N
|Section2={{Chembox Properties
| Formula = C21H29N
| MolarMass = 295.4668 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Methade, or 6-(dimethylamino)-4,4-diphenylheptane, is the parent compound of the methadone and methadol series of opioid analgesics:[1]

Chemical derivatives

The methade series includes the following compounds:

  • Acetylmethadol
    • Alphacetylmethadol
    • Levacetylmethadol
    • Betacetylmethadol)
  • Dimepheptanol (or methadol)
    • Alphamethadol
    • Betamethadol
  • Methadone
    • Levomethadone
  • Noracymethadol
  • Normethadone

Related compounds

Some related compounds include:

  • Alimadol
  • Dextromoramide
  • Dextropropoxyphene
  • Dipipanone
  • Isomethadone
  • Normethadone
  • Norpipanone
  • Phenadoxone

References

1. ^{{cite journal | author = Perrine TD, May EL | title = Synthesis of 6-dimethylamino-4,4-diphenyl-heptane and other compounds related to methadone | journal = Journal of Organic Chemistry | volume = 19 | issue = 5 | pages = 773–779 | year = 1954 | month = | pmid = | doi = 10.1021/jo01370a012| issn = 1520-6904 }}
{{amine-stub}}

1 : Amines

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