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词条 Methionine-S-oxide reductase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Methionine-S-oxide reductase
| EC_number = 1.8.4.5
| CAS_number = 70248-65-6
| IUBMB_EC_number = 1/8/4/5
| GO_code =
| image =
| width =
| caption =
}}Methionine-S-oxide reductase ({{EC number|1.8.4.5}}, methyl sulfoxide reductase I and II, acetylmethionine sulfoxide reductase, methionine sulfoxide reductase, L-methionine:oxidized-thioredoxin S-oxidoreductase) is an enzyme with systematic name L-methionine:thioredoxin-disulfide S-oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

L-methionine + thioredoxin disulfide + H2O L-methionine S-oxide + thioredoxin

In the reverse reaction, dithiothreitol can replace reduced thioredoxin.

References

1. ^{{cite journal | title = A specific enzymatic reduction of L-(-)methionine sulfoxide and a related nonspecific reduction of diulfides |author1 = Black, S. |author2 =Harte, E.M. |author3 =Hudson, B. |author4 =Wartofsky, L. |journal = J. Biol. Chem. |year = 1960 |volume = 235 |pages = 2910–2916 |pmid = }}
2. ^{{cite journal | vauthors = Ejiri SI, Weissbach H, Brot N | title = Reduction of methionine sulfoxide to methionine by Escherichia coli | journal = Journal of Bacteriology | volume = 139 | issue = 1 | pages = 161–4 | date = July 1979 | pmid = 37234 | pmc = 216841 }}
3. ^{{cite journal | vauthors = Ejiri SI, Weissbach H, Brot N | title = The purification of methionine sulfoxide reductase from Escherichia coli | journal = Analytical Biochemistry | volume = 102 | issue = 2 | pages = 393–8 | date = March 1980 | pmid = 6999943 | doi = 10.1016/0003-2697(80)90173-6 }}

External links

  • {{MeshName|Methionine-S-oxide+reductase}}
{{Sulfur oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.8.4

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