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词条 Methylecgonone reductase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Methylecgonone reductase
| EC_number = 1.1.1.334
| CAS_number =
| IUBMB_EC_number = 1/1/1/334
| GO_code =
| image =
| width =
| caption =
}}Methylecgonone reductase ({{EC number|1.1.1.334}}, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

ecgonine methyl ester + NADP+ ecgonone methyl ester + NADPH + H+

The enzyme from the plant Erythroxylum coca participates in the biosynthesis of cocaine.

References

1. ^{{cite journal | title = Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae |author1 = Jirschitzka, J. |author2 =Schmidt, G.W. |author3 =Reichelt, M. |author4 =Schneider, B. |author5 =Gershenzon, J. |author6 =D'Auria, J.C. | journal = Proc. Natl. Acad. Sci. USA |year = 2012 |volume = 109 |pages = 10304–10309 |pmid = 22665766 |doi=10.1073/pnas.1200473109 |issue=26 |pmc=3387132}}

External links

  • {{MeshName|Methylecgonone+reductase}}
{{Alcohol oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.1.1

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