词条 | Metogest |
释义 |
| IUPAC_name = 17β-Hydroxy-16,16-dimethylestr-4-en-3-one | image = Metogest.svg | CAS_number_Ref = {{cascite|correct|CAS}} | CAS_number = 52279-58-0 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = BPY4IK3W14 | ATC_prefix = None | ATC_suffix = | PubChem = 9839398 | DrugBank = | ChemSpiderID = 8015116 | C=20 | H=30 | O=2 | molecular_weight = 302.451 g/mol | SMILES = C[C@]12CC[C@H]3[C@H]([C@@H]1CC([C@@H]2O)(C)C)CCC4=CC(=O)CC[C@H]34 | StdInChI = 1S/C20H30O2/c1-19(2)11-17-16-6-4-12-10-13(21)5-7-14(12)15(16)8-9-20(17,3)18(19)22/h10,14-18,22H,4-9,11H2,1-3H3/t14-,15+,16+,17-,18-,20-/m0/s1 | StdInChIKey = JYCITEUSLNKPHC-URNBORRASA-N | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = }}Metogest (INN, USAN) (developmental code name SC-14207), also known as 16,16-dimethyl-19-nortestosterone, is a steroidal antiandrogen that was patented in 1975 and investigated as a treatment for acne but was never marketed.[1][2][3] See also
References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA816|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=816–}} {{Androgen receptor modulators}}{{steroid-stub}}{{dermatologic-drug-stub}}2. ^{{cite book|author1=R.A. Hill|author2=H.L.J. Makin|author3=D.N. Kirk|author4=G.M. Murphy|title=Dictionary of Steroids|url=https://books.google.com/books?id=qw5X0NK1A90C&pg=PA676|date=23 May 1991|publisher=CRC Press|isbn=978-0-412-27060-4|pages=676–}} 3. ^{{cite book|author1=J. Horsky|author2=J. Presl|title=Ovarian Function and its Disorders: Diagnosis and Therapy|url=https://books.google.com/books?id=7IrpCAAAQBAJ&pg=PA112|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-009-8195-9|pages=112–}} 3 : Anti-acne preparations|Estranes|Steroidal antiandrogens |
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