Mikhail Biryukov may refer to:

• Mikhail Yuryevich Biryukov (born 1958), retired Soviet and Russian football player
• Mikhail Biryukov (tennis) (born 1992), junior Russian tennis player
• Mikhail Olegovich Biryukov (born 1985), Russian ice hockey goaltender
• Mikhail Petrovich Biryukov (born 1987), Russian football player

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