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词条 Mir-186 microRNA precursor family
释义

  1. See also

  2. Further reading

  3. External links

{{Orphan|date=July 2012}}{{Infobox rfam
| Name = mir-186
| image =
| width =
| caption =
| Symbol = mir-186
| AltSymbols =
| Rfam = RF00697
| miRBase =
| miRBase_family = 14
| RNA_type = microRNA
| Tax_domain = Eukaryota;
| GO =
| SO =
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}

In molecular biology mir-186 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

See also

  • MicroRNA

Further reading

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1. ^{{Cite journal | last1 = Babenko | first1 = O. | last2 = Golubov | first2 = A. | last3 = Ilnytskyy | first3 = Y. | last4 = Kovalchuk | first4 = I. | last5 = Metz | first5 = G. A. | editor1-last = Schönbach | editor1-first = Christian | doi = 10.1371/journal.pone.0029441 | title = Genomic and Epigenomic Responses to Chronic Stress Involve miRNA-Mediated Programming | journal = PLoS ONE | volume = 7 | issue = 1 | pages = e29441 | year = 2012 | pmid = 22291890 | pmc =3265462 }}
2. ^{{Cite journal | last1 = Lv | first1 = S. Q. | last2 = Kim | first2 = Y. H. | last3 = Giulio | first3 = F. | last4 = Shalaby | first4 = T. | last5 = Nobusawa | first5 = S. | last6 = Yang | first6 = H. | last7 = Zhou | first7 = Z. | last8 = Grotzer | first8 = M. | last9 = Ohgaki | first9 = H. | doi = 10.1111/j.1750-3639.2011.00523.x | title = Genetic Alterations in MicroRNAs in Medulloblastomas | journal = Brain Pathology | volume = 22 | issue = 2 | pages = 230–239 | year = 2012 | pmid = 21793975 | pmc = }}
3. ^{{Cite journal | last1 = Goeppert | first1 = B. | last2 = Schmezer | first2 = P. | last3 = Dutruel | first3 = C. L. | last4 = Oakes | first4 = C. | last5 = Renner | first5 = M. | last6 = Breinig | first6 = M. | last7 = Warth | first7 = A. | last8 = Vogel | first8 = M. N. | last9 = Mittelbronn | first9 = M. | last10 = Mehrabi | doi = 10.1002/hep.23939 | first10 = A. | last11 = Gdynia | first11 = G. | last12 = Penzel | first12 = R. | last13 = Longerich | first13 = T. | last14 = Breuhahn | first14 = K. | last15 = Popanda | first15 = O. | last16 = Plass | first16 = C. | last17 = Schirmacher | first17 = P. | last18 = Kern | first18 = M. A. | title = Down-regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms | journal = Hepatology | volume = 52 | issue = 6 | pages = 2023–2033 | year = 2010 | pmid = 20979053 | pmc = }}
4. ^{{Cite journal | last1 = Zhang | first1 = J. | last2 = Du | first2 = Y. | last3 = Wu | first3 = C. | last4 = Ren | first4 = X. | last5 = Ti | first5 = X. | last6 = Shi | first6 = J. | last7 = Zhao | first7 = F. | last8 = Yin | first8 = H. | title = Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway | journal = Oncology Reports | volume = 24 | issue = 5 | pages = 1217–1223 | year = 2010 | pmid = 20878113 | doi=10.3892/or_00000975}}
5. ^{{Cite journal | last1 = Chen | first1 = B. Z. | last2 = Yu | first2 = S. L. | last3 = Singh | first3 = S. | last4 = Kao | first4 = L. P. | last5 = Tsai | first5 = Z. Y. | last6 = Yang | first6 = P. C. | last7 = Chen | first7 = B. H. | last8 = Shoei‑Lung Li | first8 = S. | doi = 10.1042/CBI20090081 | title = Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells | journal = Cell Biology International | volume = 35 | issue = 1 | pages = 29–37 | year = 2011 | pmid = 20735361 | pmc = }}
6. ^{{Cite journal | last1 = Tang | first1 = N. | last2 = Zhang | first2 = J. | last3 = Du | first3 = Y. | title = Curcumin promoted the apoptosis of cisplain-resistant human lung carcinoma cells A549/DDP through down-regulating miR-186* | journal = Zhongguo Fei AI Za Zhi = Chinese Journal of Lung Cancer | volume = 13 | issue = 4 | pages = 301–306 | year = 2010 | doi = 10.3779/j.issn.1009-3419.2010.04.06 | pmid = 20677554 | pmc = 6000427}}
7. ^{{Cite journal | last1 = Zhang | first1 = J. | last2 = Zhang | first2 = T. | last3 = Ti | first3 = X. | last4 = Shi | first4 = J. | last5 = Wu | first5 = C. | last6 = Ren | first6 = X. | last7 = Yin | first7 = H. | doi = 10.1016/j.bbrc.2010.07.013 | title = Curcumin promotes apoptosis in A549/DDP multidrug-resistant human lung adenocarcinoma cells through an miRNA signaling pathway | journal = Biochemical and Biophysical Research Communications | volume = 399 | issue = 1 | pages = 1–6 | year = 2010 | pmid = 20627087 | pmc = }}
8. ^{{Cite journal | last1 = Wang | first1 = K. H. | last2 = Kao | first2 = A. P. | last3 = Singh | first3 = S. | last4 = Yu | first4 = S. L. | last5 = Kao | first5 = L. P. | last6 = Yun Tsai | first6 = Z. | last7 = Lin | first7 = S. D. | last8 = Li | first8 = S. S. L. | doi = 10.1016/S1607-551X(10)70017-6 | title = Comparative Expression Profiles of mRNAs and microRNAs Among Human Mesenchymal Stem Cells Derived from Breast, Face, and Abdominal Adipose Tissues | journal = The Kaohsiung Journal of Medical Sciences | volume = 26 | issue = 3 | pages = 113–122 | year = 2010 | pmid = 20227650 | pmc = }}
9. ^{{Cite journal | last1 = Bostjancic | first1 = E. | last2 = Zidar | first2 = N. | last3 = Glavac | first3 = D. | title = MicroRNA microarray expression profiling in human myocardial infarction | journal = Disease Markers | volume = 27 | issue = 6 | pages = 255–268 | year = 2009 | doi = 10.3233/DMA-2009-0671 | pmid = 20075508 | pmc = 3834671}}
10. ^{{Cite journal | last1 = Myatt | first1 = S. S. | last2 = Wang | first2 = J. | last3 = Monteiro | first3 = L. J. | last4 = Christian | first4 = M. | last5 = Ho | first5 = K. -K. | last6 = Fusi | first6 = L. | last7 = Dina | first7 = R. E. | last8 = Brosens | first8 = J. J. | last9 = Ghaem-Maghami | first9 = S. | doi = 10.1158/0008-5472.CAN-09-1891 | last10 = Lam | first10 = E. W. F. | title = Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer | journal = Cancer Research | volume = 70 | issue = 1 | pages = 367–377 | year = 2009 | pmid = 20028871 | pmc =2880714 }}
11. ^{{Cite journal | last1 = Vinuesa | first1 = C. G. | last2 = Rigby | first2 = R. J. | last3 = Yu | first3 = D. | doi = 10.1080/08830180902934909 | title = Logic and Extent of miRNA-Mediated Control of Autoimmune Gene Expression | journal = International Reviews of Immunology | volume = 28 | issue = 3–4 | pages = 112–138 | year = 2009 | pmid = 19811318 | pmc = }}
12. ^{{Cite journal | last1 = Zhang | first1 = Y. | last2 = Li | first2 = M. | last3 = Wang | first3 = H. | last4 = Fisher | first4 = W. E. | last5 = Lin | first5 = P. H. | last6 = Yao | first6 = Q. | last7 = Chen | first7 = C. | doi = 10.1007/s00268-008-9833-0 | title = Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis | journal = World Journal of Surgery | volume = 33 | issue = 4 | pages = 698–709 | year = 2008 | pmid = 19030927 | pmc =2933040 }}
13. ^{{Cite journal | last1 = Zhou | first1 = L. | last2 = Qi | first2 = X. | last3 = Potashkin | first3 = J. A. | last4 = Abdul-Karim | first4 = F. W. | last5 = Gorodeski | first5 = G. I. | title = MicroRNAs miR-186 and miR-150 Down-regulate Expression of the Pro-apoptotic Purinergic P2X7 Receptor by Activation of Instability Sites at the 3'-Untranslated Region of the Gene That Decrease Steady-state Levels of the Transcript | doi = 10.1074/jbc.M802663200 | journal = Journal of Biological Chemistry | volume = 283 | issue = 42 | pages = 28274–28286 | year = 2008 | pmid = 18682393 | pmc =2568908 }}
14. ^{{Cite journal | last1 = Zhou | first1 = D. | last2 = Li | first2 = S. | last3 = Wen | first3 = J. | last4 = Gong | first4 = X. | last5 = Xu | first5 = L. | last6 = Luo | first6 = Y. | doi = 10.1016/j.compbiolchem.2007.08.007 | title = Genome-wide computational analyses of microRNAs and their targets from Canis familiaris | journal = Computational Biology and Chemistry | volume = 32 | issue = 1 | pages = 60–65 | year = 2008 | pmid = 18165158 | pmc = }}

External links

  • {{Rfam|id=RF00697|name=mir-186 microRNA precursor family}}
{{genetics-stub}}

2 : MicroRNA|MicroRNA precursor families

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