| 词条 | Mir-497 microRNA precursor family |
| 释义 |
| Name = mir-497 | image = | width = | caption = | Symbol = mir-497 | AltSymbols = | Rfam = RF00793 | miRBase = | miRBase_family = MIPF0000231 | RNA_type = microRNA | Tax_domain = Eukaryota; | GO = | SO = | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} In molecular biology mir-497 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. See also
Further reading1. ^{{Cite journal | last1 = Guo | first1 = S. T. | last2 = Jiang | first2 = C. C. | last3 = Wang | first3 = G. P. | last4 = Li | first4 = Y. P. | last5 = Wang | first5 = C. Y. | last6 = Guo | first6 = X. Y. | last7 = Yang | first7 = R. H. | last8 = Feng | first8 = Y. | last9 = Wang | first9 = F. H. | last10 = Tseng | first10 = H. -Y. | last11 = Thorne | first11 = R. F. | last12 = Jin | first12 = L. | last13 = Zhang | first13 = X. D. | title = MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer | doi = 10.1038/onc.2012.214 | journal = Oncogene | volume = 32 | issue = 15 | pages = 1910–1920 | year = 2012 | pmid = 22710713 | pmc =3630484 }} 2. ^{{Cite journal | last1 = Yang | first1 = C. | last2 = Wang | first2 = C. | last3 = Chen | first3 = X. | last4 = Chen | first4 = S. | last5 = Zhang | first5 = Y. | last6 = Zhi | first6 = F. | last7 = Wang | first7 = J. | last8 = Li | first8 = L. | last9 = Zhou | first9 = X. | last10 = Li | first10 = N. | last11 = Pan | first11 = H. | last12 = Zhang | first12 = J. | last13 = Zen | first13 = K. | last14 = Zhang | first14 = C. Y. | last15 = Zhang | first15 = C. | title = Identification of seven serum microRNAs from a genome-wide serum microRNA expression profile as potential noninvasive biomarkers for malignant astrocytomas | doi = 10.1002/ijc.27657 | journal = International Journal of Cancer | volume = 132 | issue = 1 | pages = 116–127 | year = 2012 | pmid = 22674182 | pmc = }} 3. ^{{Cite journal | last1 = Lajer | first1 = C. B. | last2 = Garnæs | first2 = E. | last3 = Friis-Hansen | first3 = L. | last4 = Norrild | first4 = B. | last5 = Therkildsen | first5 = M. H. | last6 = Glud | first6 = M. | last7 = Rossing | first7 = M. | last8 = Lajer | first8 = H. | last9 = Svane | first9 = D. | doi = 10.1038/bjc.2012.109 | last10 = Skotte | first10 = L. | last11 = Specht | first11 = L. | last12 = Buchwald | first12 = C. | last13 = Nielsen | first13 = F. C. | title = The role of miRNAs in human papilloma virus (HPV)-associated cancers: Bridging between HPV-related head and neck cancer and cervical cancer | journal = British Journal of Cancer | volume = 106 | issue = 9 | pages = 1526–1534 | year = 2012 | pmid = 22472886 | pmc =3341860 }} 4. ^{{Cite journal | last1 = Luense | first1 = L. J. | last2 = Veiga-Lopez | first2 = A. | last3 = Padmanabhan | first3 = V. | last4 = Christenson | first4 = L. K. | title = Developmental Programming: Gestational Testosterone Treatment Alters Fetal Ovarian Gene Expression | doi = 10.1210/en.2011-1182 | journal = Endocrinology | volume = 152 | issue = 12 | pages = 4974–4983 | year = 2011 | pmid = 22009729 | pmc =3384818 }} 5. ^{{Cite journal | last1 = Yadav | first1 = S. | last2 = Pandey | first2 = A. | last3 = Shukla | first3 = A. | last4 = Talwelkar | first4 = S. S. | last5 = Kumar | first5 = A. | last6 = Pant | first6 = A. B. | last7 = Parmar | first7 = D. | doi = 10.1074/jbc.M111.235531 | title = MiR-497 and miR-302b Regulate Ethanol-induced Neuronal Cell Death through BCL2 Protein and Cyclin D2 | journal = Journal of Biological Chemistry | volume = 286 | issue = 43 | pages = 37347–37357 | year = 2011 | pmid = 21878650 | pmc =3199482 }} 6. ^{{Cite journal | last1 = Ozata | first1 = D. M. | last2 = Caramuta | first2 = S. | last3 = Velázquez-Fernández | first3 = D. | last4 = Akçakaya | first4 = P. | last5 = Xie | first5 = H. | last6 = Höög | first6 = A. | last7 = Zedenius | first7 = J. | last8 = Bäckdahl | first8 = M. | last9 = Larsson | first9 = C. | doi = 10.1530/ERC-11-0082 | last10 = Lui | first10 = W. -O. | title = The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma | journal = Endocrine-Related Cancer | volume = 18 | issue = 6 | pages = 643–655 | year = 2011 | pmid = 21859927 | pmc =3201061 }} 7. ^{{Cite journal | last1 = Fan | first1 = X. | last2 = Jia | first2 = R. | last3 = Zhou | first3 = Y. | last4 = Song | first4 = X. | last5 = Wang | first5 = J. | last6 = Qian | first6 = G. | last7 = Ge | first7 = S. | last8 = Fan | first8 = X. | doi = 10.3892/ijo.2011.961 | title = Microarray-based analysis: Identification of hypoxia-regulated microRNAs in retinoblastoma cells | journal = International Journal of Oncology | volume = 38 | issue = 5 | pages = 1385–1393 | year = 2011 | pmid = 21373755 | pmc = }} 8. ^{{Cite journal | last1 = Balatti | first1 = V. | last2 = Maniero | first2 = S. | last3 = Ferracin | first3 = M. | last4 = Veronese | first4 = A. | last5 = Negrini | first5 = M. | last6 = Ferrocci | first6 = G. | last7 = Martini | first7 = F. | last8 = Tognon | first8 = M. G. | doi = 10.1097/JTO.0b013e31820db125 | title = MicroRNAs Dysregulation in Human Malignant Pleural Mesothelioma | journal = Journal of Thoracic Oncology | volume = 6 | issue = 5 | pages = 844–851 | year = 2011 | pmid = 21358347 | pmc = }} 9. ^{{Cite journal | last1 = Li | first1 = D. | last2 = Zhao | first2 = Y. | last3 = Liu | first3 = C. | last4 = Chen | first4 = X. | last5 = Qi | first5 = Y. | last6 = Jiang | first6 = Y. | last7 = Zou | first7 = C. | last8 = Zhang | first8 = X. | last9 = Liu | first9 = S. | last10 = Wang | doi = 10.1158/1078-0432.CCR-10-1800 | first10 = X. | last11 = Zhao | first11 = D. | last12 = Sun | first12 = Q. | last13 = Zeng | first13 = Z. | last14 = Dress | first14 = A. | last15 = Lin | first15 = M. C. | last16 = Kung | first16 = H. -F. | last17 = Rui | first17 = H. | last18 = Liu | first18 = L. -Z. | last19 = Mao | first19 = F. | last20 = Jiang | first20 = B. -H. | last21 = Lai | first21 = L. | title = Analysis of MiR-195 and MiR-497 Expression, Regulation and Role in Breast Cancer | journal = Clinical Cancer Research | volume = 17 | issue = 7 | pages = 1722–1730 | year = 2011 | pmid = 21350001 | pmc = }} 10. ^{{Cite journal | last1 = Zhu | first1 = W. | last2 = Zhu | first2 = D. | last3 = Lu | first3 = S. | last4 = Wang | first4 = T. | last5 = Wang | first5 = J. | last6 = Jiang | first6 = B. | last7 = Shu | first7 = Y. | last8 = Liu | first8 = P. | doi = 10.1007/s12032-010-9797-4 | title = MiR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2 | journal = Medical Oncology | volume = 29 | issue = 1 | pages = 384–391 | year = 2011 | pmid = 21258880 | pmc = }} 11. ^{{Cite journal | last1 = Rink | first1 = C. | last2 = Khanna | first2 = S. | doi = 10.1152/physiolgenomics.00158.2010 | title = MicroRNA in ischemic stroke etiology and pathology | journal = Physiological Genomics | volume = 43 | issue = 10 | pages = 521–528 | year = 2010 | pmid = 20841499 | pmc =3110894 }} 12. ^{{Cite journal | last1 = Finnerty | first1 = J. R. | last2 = Wang | first2 = W. X. | last3 = Hébert | first3 = S. B. S. | last4 = Wilfred | first4 = B. R. | last5 = Mao | first5 = G. | last6 = Nelson | first6 = P. T. | doi = 10.1016/j.jmb.2010.07.051 | title = The miR-15/107 Group of MicroRNA Genes: Evolutionary Biology, Cellular Functions, and Roles in Human Diseases | journal = Journal of Molecular Biology | volume = 402 | issue = 3 | pages = 491–509 | year = 2010 | pmid = 20678503 | pmc =2978331 }} 13. ^{{Cite journal | last1 = Wald | first1 = A. I. | last2 = Hoskins | first2 = E. E. | last3 = Wells | first3 = S. I. | last4 = Ferris | first4 = R. L. | last5 = Khan | first5 = S. A. | title = Alteration of microRNA profiles in squamous cell carcinoma of the head and neck cell lines by human papillomavirus | doi = 10.1002/hed.21475 | journal = Head & Neck | volume = 33 | issue = 4 | pages = 504–512 | year = 2011 | pmid = 20652977 | pmc =3080748 }} 14. ^{{Cite journal | last1 = Lehmann | first1 = U. | last2 = Streichert | first2 = T. | last3 = Otto | first3 = B. | last4 = Albat | first4 = C. | last5 = Hasemeier | first5 = B. | last6 = Christgen | first6 = H. | last7 = Schipper | first7 = E. | last8 = Hille | first8 = U. | last9 = Kreipe | first9 = H. H. | last10 = Länger | first10 = F. | title = Identification of differentially expressed microRNAs in human male breast cancer | doi = 10.1186/1471-2407-10-109 | journal = BMC Cancer | volume = 10 | pages = 109 | year = 2010 | pmid = 20331864 | pmc =2850898 }} 15. ^{{Cite journal | last1 = Lindberg | first1 = R. L. P. | last2 = Hoffmann | first2 = F. | last3 = Mehling | first3 = M. | last4 = Kuhle | first4 = J. | last5 = Kappos | first5 = L. | title = Altered expression of miR-17-5p in CD4+lymphocytes of relapsing-remitting multiple sclerosis patients | doi = 10.1002/eji.200940032 | journal = European Journal of Immunology | volume = 40 | issue = 3 | pages = 888–898 | year = 2010 | pmid = 20148420 | pmc = }} 16. ^{{Cite journal | last1 = Yin | first1 = K. J. | last2 = Deng | first2 = Z. | last3 = Huang | first3 = H. | last4 = Hamblin | first4 = M. | last5 = Xie | first5 = C. | last6 = Zhang | first6 = J. | last7 = Chen | first7 = Y. E. | doi = 10.1016/j.nbd.2009.12.021 | title = MiR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia | journal = Neurobiology of Disease | volume = 38 | issue = 1 | pages = 17–26 | year = 2010 | pmid = 20053374 | pmc =2837803 }} 17. ^{{Cite journal | last1 = Olsen | first1 = L. | last2 = Klausen | first2 = M. | last3 = Helboe | first3 = L. | last4 = Nielsen | first4 = F. C. | last5 = Werge | first5 = T. | editor1-last = Preiss | editor1-first = Thomas | title = MicroRNAs Show Mutually Exclusive Expression Patterns in the Brain of Adult Male Rats | doi = 10.1371/journal.pone.0007225 | journal = PLoS ONE | volume = 4 | issue = 10 | pages = e7225 | year = 2009 | pmid = 19806225 | pmc =2752988 }} 18. ^{{Cite journal | last1 = Guo | first1 = J. | last2 = Miao | first2 = Y. | last3 = Xiao | first3 = B. | last4 = Huan | first4 = R. | last5 = Jiang | first5 = Z. | last6 = Meng | first6 = D. | last7 = Wang | first7 = Y. | doi = 10.1111/j.1440-1746.2008.05666.x | title = Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues | journal = Journal of Gastroenterology and Hepatology | volume = 24 | issue = 4 | pages = 652–657 | year = 2009 | pmid = 19175831 | pmc = }} 19. ^{{Cite journal | last1 = Yan | first1 = L. -X. | last2 = Huang | first2 = X. -F. | last3 = Shao | first3 = Q. | last4 = Huang | first4 = M. -Y. | last5 = Deng | first5 = L. | last6 = Wu | first6 = Q. -L. | last7 = Zeng | first7 = Y. -X. | last8 = Shao | first8 = J. -Y. | doi = 10.1261/rna.1034808 | title = MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis | journal = RNA | volume = 14 | issue = 11 | pages = 2348–2360 | year = 2008 | pmid = 18812439 | pmc =2578865 }} 20. ^{{Cite journal | last1 = Flavin | first1 = R. J. | last2 = Smyth | first2 = P. C. | last3 = Laios | first3 = A. | last4 = O'Toole | first4 = S. A. | last5 = Barrett | first5 = C. | last6 = Finn | first6 = S. P. | last7 = Russell | first7 = S. | last8 = Ring | first8 = M. | last9 = Denning | first9 = K. M. | last10 = Li | doi = 10.1038/modpathol.2008.135 | first10 = J. | last11 = Aherne | first11 = S. T. | last12 = Sammarae | first12 = D. A. | last13 = Aziz | first13 = N. A. | last14 = Alhadi | first14 = A. | last15 = Sheppard | first15 = B. L. | last16 = Lao | first16 = K. | last17 = Sheils | first17 = O. M. | last18 = O'Leary | first18 = J. J. | title = Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma | journal = Modern Pathology | volume = 22 | issue = 2 | pages = 197–205 | year = 2008 | pmid = 18677302 | pmc = }} External links
2 : MicroRNA|MicroRNA precursor families |
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