| 词条 | Mitochondrial ribosomal death-associated protein 3 |
| 释义 |
| Symbol = DAP3 | Name = DAP3 | image = | width = | caption = | Pfam = PF10236 | Pfam_clan = CL0023 | InterPro = IPR019368 | SMART = | PROSITE = | MEROPS = | SCOP = | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }} In molecular biology, the mitochondrial ribosomal death-associated protein 3 family of proteins is a family of conserved proteins which were originally described as death-associated-protein-3 (DAP-3). The proteins carry a P-loop DNA-binding motif, and induce apoptosis.[1] DAP3 has been shown to be a pro-apoptotic factor in the mitochondrial matrix [2] and to be crucial for mitochondrial biogenesis and so has also been designated as MRP-S29 (mitochondrial ribosomal protein subunit 29). References1. ^{{cite journal |vauthors=Kissil JL, Cohen O, Raveh T, Kimchi A | title = Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death | journal = EMBO J. | volume = 18 | issue = 2 | pages = 353–62 |date=January 1999 | pmid = 9889192 | pmc = 1171130 | doi = 10.1093/emboj/18.2.353 | url = }} {{InterPro content|IPR019368}}2. ^{{cite journal |vauthors=Berger T, Brigl M, Herrmann JM, Vielhauer V, Luckow B, Schlondorff D, Kretzler M | title = The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins | journal = J. Cell Sci. | volume = 113 | issue = 20| pages = 3603–12 |date=October 2000 | pmid = 11017876 | doi = | url = }} 1 : Protein families |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。