词条 | Modotuximab |
释义 |
| type = mab | image = | alt = | mab_type = mab | source = xi | target = HER1 | tradename = | Drugs.com = | MedlinePlus = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 1310460-86-6 | ATC_prefix = none | ATC_suffix = | PubChem = | DrugBank = | chemical_formula = | molecular_weight = | ChemSpiderID = none | KEGG = D11125 }}Modotuximab (INN; formerly zatuximab) is a chimeric monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to HER1.[1] References1. ^{{cite journal | author = World Health Organization | title = International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 | journal = WHO Drug Information | volume = 26 | issue = 2 | year = 2012 | url = http://www.who.int/medicines/publications/druginformation/innlists/Final_PL107.pdf | format=PDF}} {{monoclonals for tumors}}{{monoclonal-antibody-stub}} 1 : Monoclonal antibodies for tumors |
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