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词条 Nadoxolol
释义

  1. References

{{Chembox
| ImageFile = Nadoxolol.svg
| ImageSize = 200px
| ImageAlt =
| IUPACName = N′,3-Dihydroxy-4-naphthalen-1-yloxybutanimidamide
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo = 54063-51-3
| CASNo1 = 35991-93-6
| CASNo1_Comment = (hydrochloride)
| PubChem = 6328253
| EINECS = 252-825-2
| ChemSpiderID = 4886543
| SMILES = C1=CC=C2C(=C1)C=CC=C2OCC(C/C(=N/O)/N)O
| InChI = 1/C14H16N2O3/c15-14(16-18)8-11(17)9-19-13-7-3-5-10-4-1-2-6-12(10)13/h1-7,11,17-18H,8-9H2,(H2,15,16)
| InChIKey = UPZVYDSBLFNMLK-UHFFFAOYAW
| StdInChI = 1S/C14H16N2O3/c15-14(16-18)8-11(17)9-19-13-7-3-5-10-4-1-2-6-12(10)13/h1-7,11,17-18H,8-9H2,(H2,15,16)
| StdInChIKey = UPZVYDSBLFNMLK-UHFFFAOYSA-N
| RTECS =
| MeSHName = C006154
}}
|Section2={{Chembox Properties
| C=14 | H=16 | N=2 | O=3
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}Nadoxolol is an antiarrhythmic agent,[1] chemically related in structure to beta-adrenergic receptor blocker drugs such as propranolol.[2]

References

1. ^Warembourg H, Ducloux G. [Clinical study of a new anti-arrhythmia agent: nadoxolol]. Lille Med. 1976;21(4 Suppl 2):386-8. {{PMID|957857}}.
2. ^{{cite journal|pmid=12818235|year=2003|last1=Kapoor|first1=M|last2=Anand|first2=N|last3=Koul|first3=S|last4=Chimni|first4=SS|last5=Manhas|first5=KS|last6=Raina|first6=C|last7=Parshad|first7=R|last8=Taneja|first8=SC|last9=Qazi|first9=GN|title=Kinetic resolution of 1-chloro-3-(1-naphthyloxy)-2-propanol, an intermediate in the synthesis of beta-adrenergic receptor blockers|volume=31|issue=3|pages=259–69|journal=Bioorganic Chemistry}}
{{Adrenergics}}{{Antiarrhythmic agents}}{{organic-compound-stub}}{{pharma-stub}}

2 : Antiarrhythmic agents|Naphthalenes

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