词条 | Nadoxolol |
释义 |
| ImageFile = Nadoxolol.svg | ImageSize = 200px | ImageAlt = | IUPACName = N′,3-Dihydroxy-4-naphthalen-1-yloxybutanimidamide | OtherNames = |Section1={{Chembox Identifiers | CASNo = 54063-51-3 | CASNo1 = 35991-93-6 | CASNo1_Comment = (hydrochloride) | PubChem = 6328253 | EINECS = 252-825-2 | ChemSpiderID = 4886543 | SMILES = C1=CC=C2C(=C1)C=CC=C2OCC(C/C(=N/O)/N)O | InChI = 1/C14H16N2O3/c15-14(16-18)8-11(17)9-19-13-7-3-5-10-4-1-2-6-12(10)13/h1-7,11,17-18H,8-9H2,(H2,15,16) | InChIKey = UPZVYDSBLFNMLK-UHFFFAOYAW | StdInChI = 1S/C14H16N2O3/c15-14(16-18)8-11(17)9-19-13-7-3-5-10-4-1-2-6-12(10)13/h1-7,11,17-18H,8-9H2,(H2,15,16) | StdInChIKey = UPZVYDSBLFNMLK-UHFFFAOYSA-N | RTECS = | MeSHName = C006154 }} |Section2={{Chembox Properties | C=14 | H=16 | N=2 | O=3 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Nadoxolol is an antiarrhythmic agent,[1] chemically related in structure to beta-adrenergic receptor blocker drugs such as propranolol.[2] References1. ^Warembourg H, Ducloux G. [Clinical study of a new anti-arrhythmia agent: nadoxolol]. Lille Med. 1976;21(4 Suppl 2):386-8. {{PMID|957857}}. {{Adrenergics}}{{Antiarrhythmic agents}}{{organic-compound-stub}}{{pharma-stub}}2. ^{{cite journal|pmid=12818235|year=2003|last1=Kapoor|first1=M|last2=Anand|first2=N|last3=Koul|first3=S|last4=Chimni|first4=SS|last5=Manhas|first5=KS|last6=Raina|first6=C|last7=Parshad|first7=R|last8=Taneja|first8=SC|last9=Qazi|first9=GN|title=Kinetic resolution of 1-chloro-3-(1-naphthyloxy)-2-propanol, an intermediate in the synthesis of beta-adrenergic receptor blockers|volume=31|issue=3|pages=259–69|journal=Bioorganic Chemistry}} 2 : Antiarrhythmic agents|Naphthalenes |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。