“NAD(P)H-hydrate epimerase”的意思、由来-开放百科全书

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NAD(P)H-hydrate epimerase

释义

References
External links

{{Infobox enzyme
| Name = NAD(P)H-hydrate epimerase
| EC_number = 5.1.99.6
| CAS_number =
| IUBMB_EC_number = 5/1/99/6
| GO_code =
| image =
| width =
| caption =
}}NAD(P)H-hydrate epimerase ({{EC number|5.1.99.6}}, NAD(P)HX epimerase) is an enzyme with systematic name (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide 6-epimerase.^[1] This enzyme catalyses the following chemical reaction

(1) (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide

(2) (6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate

The enzyme can use either (R)-NADH-hydrate or (R)-NADPH-hydrate as a substrate.

References

1. ^{{cite journal | title = Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair |author1 = Marbaix, A.Y. |author2 =Noel, G. |author3 =Detroux, A.M. |author4 =Vertommen, D. |author5 =Van Schaftingen, E. |author6 =Linster, C.L. | journal = J. Biol. Chem. |date = 2011 |volume = 286 |issue = 48 |pages = 41246–41252 |pmid = 21994945 |doi=10.1074/jbc.c111.310847 |pmc=3308837}}

External links

{{MeshName|NAD(P)H-hydrate+epimerase}}

1 : EC 5.1.99

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