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| Name = Neamine transaminase
| EC_number = 2.6.1.93
| CAS_number =
| IUBMB_EC_number = 2/6/1/93
| GO_code =
| image =
| width =
| caption =
}}Neamine transaminase ({{EC number|2.6.1.93}}, glutamate---6'-dehydroparomamine aminotransferase, btrB (gene), neoN (gene), kacL (gene)) is an enzyme with systematic name neamine:2-oxoglutarate aminotransferase.[1][2][3] This enzyme catalyses the following chemical reaction
neamine + 2-oxoglutarate6'-dehydroparomamine + L-glutamate
The reaction occurs in vivo in the opposite direction.
References
1. ^{{cite journal | vauthors = Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB | title = Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin | journal = ChemBioChem | volume = 8 | issue = 3 | pages = 283–8 | date = February 2007 | pmid = 17206729 | doi = 10.1002/cbic.200600371 }}
2. ^{{cite journal | vauthors = Clausnitzer D, Piepersberg W, Wehmeier UF | title = The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin | journal = Journal of Applied Microbiology | volume = 111 | issue = 3 | pages = 642–51 | date = September 2011 | pmid = 21689223 | doi = 10.1111/j.1365-2672.2011.05082.x }}
3. ^{{cite journal | vauthors = Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ | title = Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation | journal = Nature Chemical Biology | volume = 7 | issue = 11 | pages = 843–52 | date = October 2011 | pmid = 21983602 | doi = 10.1038/nchembio.671 }}
2. ^{{cite journal | vauthors = Clausnitzer D, Piepersberg W, Wehmeier UF | title = The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin | journal = Journal of Applied Microbiology | volume = 111 | issue = 3 | pages = 642–51 | date = September 2011 | pmid = 21689223 | doi = 10.1111/j.1365-2672.2011.05082.x }}
3. ^{{cite journal | vauthors = Park JW, Park SR, Nepal KK, Han AR, Ban YH, Yoo YJ, Kim EJ, Kim EM, Kim D, Sohng JK, Yoon YJ | title = Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation | journal = Nature Chemical Biology | volume = 7 | issue = 11 | pages = 843–52 | date = October 2011 | pmid = 21983602 | doi = 10.1038/nchembio.671 }}
External links
- {{MeshName|Neamine+transaminase}}
1 : EC 2.6.1
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