| 词条 | N,N-Dimethylethylamine |
| 释义 |
| Watchedfields = changed | verifiedrevid = 607448118 | Name = | ImageFile = N,N-Dimethylethylamine.svg | ImageSize = | PIN = N,N-Dimethyl ethyl amine | SystematicName = | OtherNames = Ethyl(dimethyl)amine | IUPACName = Dimethyl ethyl amine | Section1 = {{Chembox Identifiers | IUPHAR_ligand = 5523 | CASNo_Ref = {{cascite|correct|??}} | CASNo=598-56-1 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 11230 | PubChem=11723 | SMILES=CCN(C)C | Section2 = {{Chembox Properties | C=4 | H=11 | N=1 | Appearance=Volatile liquid at room temp. | Density= 0.7±0.1 g/cm3 | MeltingPtC=-140 | BoilingPtC= 36.5 | Solubility= | VaporPressure = 495.4±0.1 mmHg | pKa = 10.16 (for the conjugate acid) (H2O)[1] | Section3 = {{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = | Section4 = | Section5 = | Section6 = }}N,N-Dimethylethylamine (DMEA), sometimes referred to as dimethylethylamine, is an organic compound with formula {{chemical formula|C|4|H|11|N}}. It is an industrial chemical that is mainly used in foundries as a catalyst for sand core production.[1] Dimethylethylamine is a malodorous, volatile liquid at room temperature that is excreted at greater concentrations with larger dietary intake of trimethylamine.[2] It has recently been identified as an agonist of human trace amine-associated receptor 5.[3] See also
References1. ^{{cite web|title=Dimethylethylamine|url=http://www.basf.com/group/corporate/us/en/brand/N_N_DIMETHYLETHYLAMINE|publisher=BASF The Chemical Company|accessdate=4 May 2014}} {{TAAR ligands}}{{DEFAULTSORT:Dimethylethylamine, N, N-}}{{amine-stub}}2. ^1 {{cite web|title=N,N-Dimethylethylamine|url=http://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+5712|work=Toxnet|publisher=Hazardous Substance Data Bank|accessdate=4 May 2014|quote=The aim was to study the effect of trimethylamine (TMA) on the metabolism of the industrial catalyst N,N-dimethylethylamine to ascertain whether biological monitoring of industrial exposure to N,N-dimethylethylamine is compromised and excretion of the malodorous N,N-dimethylethylamine in sweat and urine is increased by dietary intake of TMA....Although the increased urinary and hidrotic excretion of N,N-dimethylethylamine may contribute to body odor problems, they were primarily due to TMA excretion, which is much the greater.}} 3. ^{{cite journal |vauthors=Wallrabenstein I, Kuklan J, Weber L, Zborala S, Werner M, Altmüller J, Becker C, Schmidt A, Hatt H, Hummel T, Gisselmann G |title=Human trace amine-associated receptor TAAR5 can be activated by trimethylamine |journal=PLoS ONE |volume=8 |issue=2 |pages=e54950 |year=2013 |pmid=23393561 |pmc=3564852 |doi=10.1371/journal.pone.0054950 |url=}} 2 : Alkylamines|Foul-smelling chemicals |
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