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词条 Nordinone
释义

  1. References

{{Chembox
| ImageFile = Nordinone.svg
| ImageSize = 200px
| ImageAlt =
| IUPACName = (8R,9S,10R,11R)-11-Hydroxy-10,17,17-trimethyl-1,2,6,7,8,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo = 33122-60-0
| PubChem = 3033958
| ChemSpiderID = 2298522
| InChI=1S/C20H28O2/c1-19(2)8-7-14-15-5-4-12-10-13(21)6-9-20(12,3)18(15)17(22)11-16(14)19/h10,15,17-18,22H,4-9,11H2,1-3H3/t15-,17+,18+,20-/m0/s1
| InChIKey= ALFAUJVLIRDQGD-MMTROXRISA-N
| SMILES = C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@@H](CC4=C3CCC4(C)C)O}}
|Section2={{Chembox Properties
| C=20 | H=28 | O=2
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}Nordinone (INN), also known as 11α-hydroxy-17,17-dimethyl-18-norandrosta-4,13-dien-3-one, is a naturally occurring steroid with antiandrogen properties isolated as a metabolite from the fungus Monocillium nordinii.[1][2]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA647|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=647–}}
2. ^{{cite journal|last1=Aver|first1=William A.|last2=Peña-Rodriguez|first2=Luis|title=Minor metabolites of Monocillium nordinii|journal=Phytochemistry|volume=26|issue=5|year=1987|pages=1353–1355|issn=0031-9422|doi=10.1016/S0031-9422(00)81811-7}}
{{Androgen receptor modulators}}{{steroid-stub}}

2 : Gonanes|Steroidal antiandrogens

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