词条 | Nordinone |
释义 |
| ImageFile = Nordinone.svg | ImageSize = 200px | ImageAlt = | IUPACName = (8R,9S,10R,11R)-11-Hydroxy-10,17,17-trimethyl-1,2,6,7,8,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-3-one | OtherNames = |Section1={{Chembox Identifiers | CASNo = 33122-60-0 | PubChem = 3033958 | ChemSpiderID = 2298522 | InChI=1S/C20H28O2/c1-19(2)8-7-14-15-5-4-12-10-13(21)6-9-20(12,3)18(15)17(22)11-16(14)19/h10,15,17-18,22H,4-9,11H2,1-3H3/t15-,17+,18+,20-/m0/s1 | InChIKey= ALFAUJVLIRDQGD-MMTROXRISA-N | SMILES = C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@@H](CC4=C3CCC4(C)C)O}} |Section2={{Chembox Properties | C=20 | H=28 | O=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Nordinone (INN), also known as 11α-hydroxy-17,17-dimethyl-18-norandrosta-4,13-dien-3-one, is a naturally occurring steroid with antiandrogen properties isolated as a metabolite from the fungus Monocillium nordinii.[1][2] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA647|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=647–}} {{Androgen receptor modulators}}{{steroid-stub}}2. ^{{cite journal|last1=Aver|first1=William A.|last2=Peña-Rodriguez|first2=Luis|title=Minor metabolites of Monocillium nordinii|journal=Phytochemistry|volume=26|issue=5|year=1987|pages=1353–1355|issn=0031-9422|doi=10.1016/S0031-9422(00)81811-7}} 2 : Gonanes|Steroidal antiandrogens |
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