| 词条 | Notholaenic acid |
| 释义 |
| ImageFile = Notholaenic acid.svg | ImageSize = | ImageAlt = Chemical structure of notholaenic acid | IUPACName = 2-hydroxy-4-methoxy-6-[2-(4-methoxyphenyl)ethyl]benzoic acid | OtherNames = |Section1={{Chembox Identifiers | CASNo = 72578-97-3 | InChI = 1S/C17H18O5/c1-21-13-7-4-11(5-8-13)3-6-12-9-14(22-2)10-15(18)16 (12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20) | InChIKey = QTSHPXKETKYZMV-UHFFFAOYSA-N | PubChem = 3085829 | SMILES = COC1=CC=C(C=C1)CCC2=CC(=CC(=C2C(=O)O)O)OC | ChemSpiderID = 2342609 | StdInChI = 1S/C17H18O5/c1-21-13-7-4-11(5-8-13)3-6-12-9-14(22-2)10-15(18)16(12)17(19)20/h4-5,7-10,18H,3,6H2,1-2H3,(H,19,20) | StdInChIKey = QTSHPXKETKYZMV-UHFFFAOYSA-N |Section2={{Chembox Properties | C=17 | H=18 | O=5 | Appearance = | Density = | MeltingPtC = 149 to 150 | MeltingPt_notes = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Notholaenic acid is a dihydrostilbenoid found in the farina of some ferns of the genus Notholaena.[1] It has been shown to have anti-HSV-1 (Herpes simplex virus 1) activity at high concentrations in vitro.[2] It was artificially synthesized, starting from 3-benzyloxy-5-methoxybenzyl alcohol, in 1985.[3] References1. ^{{cite journal | last1=Wollenweber | first1=Eckhard | last2=Favre-Bonvin | first2=Jean | title=Novel dihydrostilbene from fronds of Notholaena dealbata and Notholaena limitanea | journal=Phytochemistry | year=1979 | volume=18 | issue=7 | pages=1243–1244 | doi=10.1016/0031-9422(79)80153-3}} {{Dihydrostilbenoid}}{{Natural phenol-stub}}2. ^{{cite journal|last=Rinehart|first=Kenneth L. |author2=Tom G. Holt |author3=Nancy L. Fregeau |author4=Paul A. Keifer |author5=George Robert Wilson |author6=Thomas J. Perun Jr |author7=Ryuichi Sakai |author8=Anthony G. Thompson |author9=Justin G. Stroh |author10=Lois S. Shield |author11=David S. Seigler |author12=Li H. Li |author13=David G. Martin |author14=Cornelis J. P. Grimmelikhuijzen |author15=Gerd Gäde |title=Bioactive Compounds from Aquatic and Terrestrial Sources|journal=Journal of Natural Products|date=July–August 1990|volume=53|issue=4 |pages=771–792|doi=10.1021/np50070a001}} 3. ^{{cite journal | title=Total Synthesis of Notholaenic Acid | first1=Farouk S. | last1=El-Feraly | first2=Steve F. | last2=Cheatham | first3=James D. | last3=McChesney | journal=Journal of Natural Products | year=1985 | volume=48 | issue=2 | pages=293–298 | doi= 10.1021/np50038a015}} 1 : Dihydrostilbenoids |
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