| 词条 | O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase |
| 释义 |
| Name = O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase | EC_number = 2.9.1.2 | CAS_number = | IUBMB_EC_number = 2/9/1/2 | GO_code = | image = 3bcb.jpg | width = 270 | caption = Selenocysteine synthase tetramer, Mus musculus }}O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase ({{EC number|2.9.1.2}}, MMPSepSecS, SepSecS, SLA/LP, O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase, O-phospho-L-seryl-tRNA:L-selenocysteinyl-tRNA synthase) is an enzyme with systematic name selenophosphate:O-phospho-L-seryl-tRNASec selenium transferase.[1][2][3][4] This enzyme catalyses the following chemical reaction O-phospho-L-seryl-tRNASec + selenophosphate {{eqm}} L-selenocysteinyl-tRNASec + phosphate This enzyme is pyridoxal-phosphate protein. References1. ^{{cite journal | vauthors = Palioura S, Sherrer RL, Steitz TA, Söll D, Simonovic M | title = The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation | journal = Science | volume = 325 | issue = 5938 | pages = 321–5 | date = July 2009 | pmid = 19608919 | pmc = 2857584 | doi = 10.1126/science.1173755 }} 2. ^{{cite journal | vauthors = Araiso Y, Palioura S, Ishitani R, Sherrer RL, O'Donoghue P, Yuan J, Oshikane H, Domae N, Defranco J, Söll D, Nureki O | title = Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation | journal = Nucleic Acids Research | volume = 36 | issue = 4 | pages = 1187–99 | date = March 2008 | pmid = 18158303 | pmc = 2275076 | doi = 10.1093/nar/gkm1122 }} 3. ^{{cite journal | vauthors = Aeby E, Palioura S, Pusnik M, Marazzi J, Lieberman A, Ullu E, Söll D, Schneider A | title = The canonical pathway for selenocysteine insertion is dispensable in Trypanosomes | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 106 | issue = 13 | pages = 5088–92 | date = March 2009 | pmid = 19279205 | pmc = 2664009 | doi = 10.1073/pnas.0901575106 }} 4. ^{{cite journal | vauthors = Yuan J, Palioura S, Salazar JC, Su D, O'Donoghue P, Hohn MJ, Cardoso AM, Whitman WB, Söll D | title = RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 103 | issue = 50 | pages = 18923–7 | date = December 2006 | pmid = 17142313 | pmc = 1748153 | doi = 10.1073/pnas.0609703104 }} External links
1 : EC 2.9.1 |
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