PA22 may refer to:

• Payen PA-22, a French experimental aircraft
• Pennsylvania Route 22 (1920s)
• Pennsylvania's 22nd congressional district
• Piper PA-22 Tri-Pacer, an American light aircraft
• U.S. Route 22 in Pennsylvania

• Ogg–Shafarevich formula
• Oghab F.C.
• Oghab Shiraz F.C.
• Ogham characters
• Ogham Irish language
• Ogham (script)
• Ogham (Unicode block)
• Ogh Awarrangg language
• Oghi (distilled beverage)
• Oghilbeyk
• Oghlan Tappeh
• Oghlu
• Ogh Mulak
• Oghogho Oduokpe
• Oghol Beyg
• Ogholbeyg
• Ogholbeyg-e Bala
• Oghol Beyg-e Pa'in
• Oghol Beyg-e Pain
• Ogholbeyk
• Ogholbeyk-e Duzkand
• Ogholbeyk-e Olya
• Ogho-Oghene Omano Egwero
• Oghor-hai
• Oghul Beyg