| 词条 | Patricia DeCoursey |
| 释义 |
Patricia (Jackson) DeCoursey is a leading researcher in the field of chronobiology. Her research focuses on behavioral, physiological, and ecological aspects of mammalian circadian rhythms.[1][2] She is credited with creating the first Phase Response Curve (PRC). PRC’s are used throughout the field today to help illustrate the change of a biological oscillation in response to an external stimulus.[3] She currently works as a biology professor at the University of South Carolina (USC). BiographyAt an early age, DeCoursey expressed much interest in nature. She became fascinated with the outdoors though traveling with her father, a physician, and the rest of her family to remote wilderness areas [4] While attending Hunter College High School in New York City she began collecting data on the songbirds of a hardwood forest in Long Island. She mapped the number and location of the birds as well as their distinctive calls. She entered this project in the 1950 Westinghouse Science Talent Search and was named a finalist along with her twin sister Cynthia (Jackson) Fisher.[5] EducationDeCoursey's interest in ornithology led her to Cornell University, where she received a degree in zoology in 1954. She met George DeCoursey, at Cornell University, where he was a student at the time. She married George DeCoursey in 1954. DeCoursey furthered her education at the University of Wisconsin, Madison where she earned a Ph.D. in zoology and biochemistry. She did postdoctoral research with Jürgen Aschoff at the Max-Planck Institute for Behavioral Physiology in Erling-Andech, Germany for two years. She then continued her research at Washington State University,[5] CareerShe is currently a distinguished professor of biology at University of South Carolina where she has continued to further her research on mammalian circadian rhythms since she moved there with her husband in 1966.[2] Contributions to chronobiologyPhase Response CurveDecoursey is credited with the first published Phase Response Curve (PRC). The relevant paper was about flying squirrels kept in constant darkness and how they would respond to different pulses of light at different times of the day. The compilation of this data produced the first PRC.[6] Mammalian Entrainment SystemDeCoursey was the first scientists to show that the mammalian clocks can be reset by light pulses. She also showed that the photoreceptive system responsible for entrainment is different from the system involved in visual image perception.[7] Adaptive ValueDeCoursey helped the scientific world understand the adaptive value of the mammalian biological clocks (found within the suprachiasmatic nucleus (SCN)). From April 1997-October 1998 she set up an enclosure for approximately 74 chipmunks. 30 chipmunks had lesions in their SCN, 24 others were surgical control and 20 others were intact controls. After 80 days she showed that the majority of the chipmunks killed by predators had lesions in their SCN. This gave evidence to support that having a mammalian circadian clock is a favorable trait that has been naturally selected for.[8] In an outdoor enclosure, DeCoursey released white-tailed antelope ground squirrels which had various levels of SCN lesioned. The squirrels displaying the most activity during the night had the highest amount of lesioning.[9] This research has helped further our understanding of sleep related issues affecting humans such as jet lag or insomnia. Current researchHer current research focuses on the physiological and behavioral aspects of circadian rhythms, She has studied how the retina moves in response to the daily rhythm. Also, as mentioned above, her work on chipmunks has helped uncover the adaptive value of the circadian clock in the wild. She has done experiment related to the adaptive value of clocks on antelope squirrels and golden-mantled squirrels. This research furthers our understanding of sleep related issues affecting humans such as jet lag or insomnia.[1] Other achievementsDeCoursey received the 2011 South Carolina Environmental Awareness Award for re-foresting the W. Gordon Belser Arboretum at the University of South Carolina, a six-year initiative she led, as well as for various small gardens around the university. The arboretum is designated as an outdoor field classroom and laboratory for USC undergraduates, and it is also used for conducting a variety of educational outreach programs.[10] According to an article in Scientific American, DeCoursey “spends half her work time on the restoring the arboretum and organizing class visits, and the other half on her professorial duties.” [5] Decoursey also became a member of the original Organizing Committees for both the Journal of Biological Rhythms and the Society for Research on Biological Rhythms (SRBR). She has been an active member on the Advisory Board for both groups and served two terms as SRBR’’s Secretary. DeCoursey was one of the activists who worked to create what is now the Congaree National Park. Selected publications
References1. ^1 DeCoursey’s Textbook: Summary & About the Authors 2. ^1 {{cite web|title=Patricia J. DeCoursey SC Faculty Page|url=http://www.biol.sc.edu/DeCoursey|accessdate=4/8/13}} 3. ^{{cite journal|last=Johnson|first=Carl|author2=Ken-ichi, Sato Honma|title=Phase Response Curves: What Can They Tell Us about Circadian Clocks ?|journal=Circadian Clocks from Cell to Human|year=1992|pages=209–249|url=http://as.vanderbilt.edu/johnsonlab/prcatlas/carltext/|accessdate=4/8/13}} 4. ^{{cite news|last=Monk|first=John|title=USC professor wins big environmental award|url=http://www.thestate.com/2012/04/27/2252461/the-belser-arboretum-is-open-to.html|accessdate=25 April 2013|newspaper=The State|date=April 27, 2012}} 5. ^1 2 {{cite news|last=Vanderkam|first=Laura|title=For Patricia DeCoursey, When It Comes to Biology, Timing Is Everything|url=http://www.scientificamerican.com/article.cfm?id=patricia-decoursey-biology-westinghouse|accessdate=21 April 2013|newspaper=Scientificamerican|date=July 27, 2009}} 6. ^Zivkovic, Bora; aka "Coturnix" (2007). "Clock Tutorial #3c - Darwin On Time". A Blog Around the Clock. ScienceBlogs LLC) 7. ^{{cite journal|last=DeCoursey|first=Patricia|author2=Takahashi JS |author3=Bauman L |author4=Menaker M |title=Spectral sensitivity of a novel photoreceptive system mediating entrainment of mammalian circadian rhythms.|journal=Nature|date=Mar 8, 1984|volume=308|issue=5955|pages=186–8|pmid=6700721|doi=10.1038/308186a0}} 8. ^{{cite journal|last=DeCoursey|first=Patricia|author2=Walker JK |author3=Smith SA. |title=A circadian pacemaker in free-living chipmunks: essential for survival?|journal=J Comp Physiol A|date=February 2000|volume=186|issue=2|pages=168–80|doi=10.1007/s003590050017|pmid=10707315}} 9. ^{{cite journal|last=DeCoursey|first=Patricia|author2=Jill R Krulas |author3=Gary Mele |author4=Daniel C Holley |title=Circadian Performance of Suprachiasmatic Nuclei (SCN)-Lesioned Antelope Ground Squirrels in a Desert Enclosure|journal=Physiology & Behavior|date=November 1997|volume=62|issue=5|pages=1099–1108|doi=10.1016/S0031-9384(97)00263-1}} 10. ^{{cite news|title=USC professor wins 2011 Environmental Awareness Award|url=http://www.dnr.sc.gov/news/yr2012/april26/april26_awareness.html|accessdate=13 April 2013|newspaper=Life's Better Outdoors: South Carolina Department of Natural Resources|date=26 April 2012}} External links
7 : Living people|21st-century American biologists|Chronobiologists|Year of birth missing (living people)|Cornell University alumni|University of Wisconsin–Madison alumni|University of South Carolina faculty |
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