Penick is a surname. Notable people with the surname include:

• Charles Clifton Penick (1843–1914), American Anglican bishop
• Harvey Penick (1904–1995), American golfer and coach
• John Penick (1944-), American science educator and scholar

• John Moyes (cricketer)
• John Moylan
• John Moylan (footballer)
• John Moyle
• John Moyle (British Army officer)
• John Moyle (disambiguation)
• John (Moz) Farnsworth
• John M. Palms
• John M. Parker (New York)
• John M. P. Atkinson
• John M. Patterson School
• John M. Pearson
• John M. Peters
• John M. Pfau Library
• John M Pfau Library
• John M. Philbrook House
• John M. Pickard
• John M. Pierce House
• John M. Potter
• John Mrakov
• John M. Reed
• John M. Reeves Student Recreation Center
• John M. Richardson
• John M. Richardson (admiral)
• John M. Riggs (soldier)