“Pentalenolactone F synthase”的意思、由来-开放百科全书

词条

Pentalenolactone F synthase

释义

References
External links

{{Infobox enzyme
| Name = Pentalenolactone F synthase
| EC_number = 1.14.11.36
| CAS_number =
| IUBMB_EC_number = 1/14/11/36
| GO_code =
| image =
| width =
| caption =
}}Pentalenolactone F synthase ({{EC number|1.14.11.36}}, PEND (gene), PNTD (gene), PTLD (gene)) is an enzyme with systematic name pentalenolactone-D,2-oxoglutarate:oxygen oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

pentalenolactone D + 2 2-oxoglutarate + 2 O₂ pentalenolactone F + 2 succinate + 2 CO₂ + H₂O (overall reaction)

(1a) pentalenolactone D + 2-oxoglutarate + O₂ pentalenolactone E + succinate + CO₂ + H₂O

(1b) pentalenolactone E + 2-oxoglutarate + O₂ pentalenolactone F + succinate + CO₂

Pentalenolactone F synthase contains Fe(II), and ascorbate is needed for its action.

References

1. ^{{cite journal | vauthors = Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE | title = Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone | journal = Biochemistry | volume = 50 | issue = 10 | pages = 1739–54 | date = March 2011 | pmid = 21250661 | pmc = 3051010 | doi = 10.1021/bi1019786 }}

External links

{{MeshName|Pentalenolactone+F+synthase}}

1 : EC 1.14.11

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