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词条 Perakine reductase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Perakine reductase
| EC_number = 1.1.1.317
| CAS_number =
| IUBMB_EC_number = 1/1/1/317
| GO_code =
| image =
| width =
| caption =
}}Perakine reductase ({{EC number|1.1.1.317}}) is an enzyme with systematic name raucaffrinoline:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

raucaffrinoline + NADP+ perakine + NADPH + H+

The biosynthesis of raucaffrinoline from perakine is a side route of the ajmaline biosynthesis pathway.

References

1. ^{{cite journal | vauthors = Sun L, Ruppert M, Sheludko Y, Warzecha H, Zhao Y, Stöckigt J | title = Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia | journal = Plant Molecular Biology | volume = 67 | issue = 5 | pages = 455–67 | date = July 2008 | pmid = 18409028 | doi = 10.1007/s11103-008-9331-7 }}
2. ^{{cite journal | vauthors = Rosenthal C, Mueller U, Panjikar S, Sun L, Ruppert M, Zhao Y, Stöckigt J | title = Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants | journal = Acta Crystallographica. Section F, Structural Biology and Crystallization Communications | volume = 62 | issue = Pt 12 | pages = 1286–9 | date = December 2006 | pmid = 17142919 | pmc = 2225361 | doi = 10.1107/S174430910605041X }}

External links

  • {{MeshName|Perakine+reductase}}
{{Alcohol oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.1.1

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