词条 | Phenethyl isothiocyanate |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 480479568 | ImageFile = Phenethyl isothiocyanate.svg | ImageSize = 150px | ImageFileL2 = Phenethyl isothiocyanate-3D-balls-by-AHRLS-2012.png | ImageSizeL2 = 150px | ImageFileR2 = Phenethyl isothiocyanate-3D-vdW-by-AHRLS-2012.png | ImageSizeR2 = 150px | IUPACName = (2-Isothiocyanatoethyl)benzene | OtherNames = Phenylethyl isothiocyanate; Phenethyl mustard oil |Section1={{Chembox Identifiers | Abbreviations = PEITC | CASNo = 2257-09-2 | CASNo_Ref = {{cascite|changed|??}} | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 151649 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 351346 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 6U7TFK75KV | PubChem = 16741 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 15870 | SMILES = S=C=N/CCc1ccccc1 | InChI = 1/C9H9NS/c11-8-10-7-6-9-4-2-1-3-5-9/h1-5H,6-7H2 | InChIKey = IZJDOKYDEWTZSO-UHFFFAOYAB | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C9H9NS/c11-8-10-7-6-9-4-2-1-3-5-9/h1-5H,6-7H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = IZJDOKYDEWTZSO-UHFFFAOYSA-N |Section2={{Chembox Properties | C=9 | H=9 | N=1 | S=1 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Phenethyl isothiocyanate (PEITC) is a naturally occurring isothiocyanate whose precursor, gluconasturtiin is found in some cruciferous vegetables,[1] especially watercress. PEITC has been studied for its potential for chemoprevention of cancers,[2][3] such as prostate cancer.[4] In terms of biosynthesis, PEITC is produced from gluconasturtiin by the action of the enzyme myrosinase. References1. ^{{cite web | url = http://www.cancer.gov/dictionary?cdrid=44447 | title = Dictionary of Cancer Terms: PEITC | publisher = National Cancer Institute}} {{Cruciferous Biochemistry}}2. ^{{Cite journal | pmid = 20013083 | year = 2010 | last1 = Cheung | first1 = KL | last2 = Kong | first2 = AN | title = Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention | volume = 12 | issue = 1 | pages = 87–97 | doi = 10.1208/s12248-009-9162-8 | pmc = 2811646 | journal = The AAPS Journal}} 3. ^{{cite journal |author1=Kwon, Ki Han |author2=Xu, Changjiang |author3=Keum, Young-Sam |author4=Khor, Tin Oo |author5=Kim, Jung-Hwan |author6=Huang, Mou-Tuan |author7=Reddy, Bandaru S. |author8=Li, Wenge |author9=Kong, Ah-Ng Tony | title = Natural dietary phytochemicals: a promising future for cancer prevention and treatment of earlier lesion | journal = Cancer: Disease Progression and Chemoprevention | year = 2007 | pages = 109–126}} 4. ^{{Cite journal | pmid = 20664922 | year = 2010 | last1 = Wang | first1 = LG | last2 = Chiao | first2 = JW | title = Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review) | volume = 37 | issue = 3 | pages = 533–9 | journal = International Journal of Oncology | doi=10.3892/ijo_00000702}} 1 : Isothiocyanates |
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