| 词条 | Phlorofucofuroeckol A |
| 释义 |
| Name = Phlorofucofuroeckol A | ImageFile = Phlorofucofuroeckol A.png | ImageName = Chemical structure of phlorofucofuroeckol A | ImageAlt = Chemical structure of phlorofucofuroeckol A | IUPACName = 4,9-bis(3,5-dihydroxyphenoxy)-[1]benzofuro[3,2-a]oxanthrene-1,3,6,10,12-pentol | OtherNames = |Section1={{Chembox Identifiers | CASNo = 128129-56-6 | CASNo_Ref = | CASNoOther = | ChEMBL_Ref = | ChEMBL = 510508 | ChemSpiderID = 115819 | PubChem = 130976 | SMILES = C1=C(C=C(C=C1O)OC2=C(C=C(C3=C2OC4=CC(=C5C(=C43)OC6=C(O5)C(=C(C=C6O)O)OC7=CC(=CC(=C7)O)O)O)O)O)O | InChI = 1S/C30H18O14/c31-10-1-11(32)4-14(3-10)40-24-17(36)7-16(35)22-23-21(42-28(22)24)9-20(39)25-29(23)43-27-19(38)8-18(37)26(30(27)44-25)41-15-5-12(33)2-13(34)6-15/h1-9,31-39H | InChIKey = SLWPBUMYPRVYIJ-UHFFFAOYSA-N | StdInChI = | StdInChIKey = | MeSHName = |Section2={{Chembox Properties | Formula = C30H18O14 | MolarMass = 602.45 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }}Phlorofucofuroeckol A is a phlorotannin isolated from brown algae species such as Eisenia bicyclis (an edible seaweed called arame in Japan),[1] Ecklonia cava,[2] Ecklonia kurome[3] or Ecklonia stolonifera.[4] The molecule possesses both the dibenzo-1,4-dioxin and dibenzofuran elements.[3] References1. ^{{Cite journal|doi=10.1002/jsfa.5585|pmid=22271637|title=Α-Glucosidase- and α-amylase-inhibitory activities of phlorotannins from Eisenia bicyclis|year=2012|last1=Eom|first1=Sung-Hwan|last2=Lee|first2=Sang-Hoon|last3=Yoon|first3=Na-Young|last4=Jung|first4=Won-Kyo|last5=Jeon|first5=You-Jin|last6=Kim|first6=Se-Kwon|last7=Lee|first7=Myung-Suk|last8=Kim|first8=Young-Mog|journal=Journal of the Science of Food and Agriculture|volume=92|issue=10|pages=2084–90}} {{phlorotannin}}{{Natural-phenol-stub}}2. ^{{Cite journal|pmid=15056863|year=2004|last1=Ahn|first1=MJ|last2=Yoon|first2=KD|last3=Min|first3=SY|last4=Lee|first4=JS|last5=Kim|first5=JH|last6=Kim|first6=TG|last7=Kim|first7=SH|last8=Kim|first8=NG|last9=Huh|first9=H|last10=Kim|first10=J|title=Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava|volume=27|issue=4|pages=544–7|journal=Biological & Pharmaceutical Bulletin|doi=10.1248/bpb.27.544}} 3. ^1 {{Cite journal|pmid=2337936|year=1990|last1=Fukuyama|first1=Y|last2=Kodama|first2=M|last3=Miura|first3=I|last4=Kinzyo|first4=Z|last5=Mori|first5=H|last6=Nakayama|first6=Y|last7=Takahashi|first7=M|title=Anti-plasmin inhibitor. VI. Structure of phlorofucofuroeckol A, a novel phlorotannin with both dibenzo-1,4-dioxin and dibenzofuran elements, from Ecklonia kurome Okamura|volume=38|issue=1|pages=133–5|journal=Chemical & Pharmaceutical Bulletin|doi=10.1248/cpb.38.133}} 4. ^{{Cite journal|pmid=21963823|year=2011|last1=Kim|first1=AR|last2=Lee|first2=MS|last3=Shin|first3=TS|last4=Hua|first4=H|last5=Jang|first5=BC|last6=Choi|first6=JS|last7=Byun|first7=DS|last8=Utsuki|first8=T|last9=Ingram|first9=D|last10=Kim|first10=HR|title=Phlorofucofuroeckol a inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK|volume=25|issue=8|pages=1789–95|doi=10.1016/j.tiv.2011.09.012|journal=Toxicology in Vitro}} 1 : Phlorotannins |
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