请输入您要查询的百科知识:

 

词条 Phorate
释义

  1. Overview

  2. Toxicity

  3. References

  4. External links

{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 445856103
| ImageFile = Phorate.svg
| ImageSize = 200px
| IUPACName = O,O-Diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate
| OtherNames = Thimet (trademark)
3911 (trademark)
|Section1={{Chembox Identifiers
| CASNo = 298-02-2
| CASNo_Ref = {{cascite|correct|CAS}}
| PubChem = 4790
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4626
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 38764
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 510014
| SMILES = S=P(OCC)(SCSCC)OCC
| InChI = 1/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3
| InChIKey = BULVZWIRKLYCBC-UHFFFAOYAA
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = BULVZWIRKLYCBC-UHFFFAOYSA-N
|Section2={{Chembox Properties
| C=7 | H=17 | O=2 | P=1 | S=3
| Appearance = Colorless liquid
| Odor = Skunk-like[1]
| Density = 1.16 g/mL
| MeltingPtF = -45
| MeltingPt_notes = [1]
| BoilingPt = 118-120°C (2.0 mm Hg)[1]
| Solubility = 0.005% (20°C)[1]
| VaporPressure = 0.0008 mmHg (20°C)[1]
|Section3={{Chembox Hazards
| MainHazards =
| FlashPtF = 320
| FlashPt_notes = (open cup)[1]
| AutoignitionPt =
| PEL = none[2]
| IDLH = N.D.[2]
| REL = TWA 0.05 mg/m3 ST 0.2 mg/m3 [skin][2]
}}

Phorate is an organophosphate used as an insecticide and acaricide.

Overview

At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including human. It inhibits acetylcholinesterase and butyrylcholinesterase.[3]

Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.[3]

Toxicity

Phorate is absorbed readily through all ways. Its toxicity is high. Oral LD50 to rats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.[3]

References

1. ^Farm Chemicals Handbook, Meister Publishing Co., Willoughby, OH (1991)
2. ^{{PGCH|0502}}
3. ^Data sheets on pesticides No. 75 – Phorate

External links

  • {{PPDB|519}}
{{Insecticides}}{{Acetylcholine metabolism and transport modulators}}

3 : Acetylcholinesterase inhibitors|Organophosphate insecticides|Organosulfur compounds

随便看

 

开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。

 

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间:2024/9/21 10:41:17