“Phthalide”的意思、由来-开放百科全书

词条

Phthalide

释义

Uses
Examples
References

{{Chembox
| ImageFile = Phthalide.svg
| ImageSize = 150px
| IUPACName = 2-Benzofuran-1(3H)-one
| OtherNames = Phthalolactone
|Section1={{Chembox Identifiers
| CASNo = 87-41-2
| CASNo_Ref = {{cascite|correct|}}
| UNII = 8VV922U86J
| PubChem = 6885
| ChemSpiderID = 6621
| ChEBI = 38085
| SMILES = O=C1OCc2ccccc12
| InChI = 1/C8H6O2/c9-8-7-4-2-1-3-6(7)5-10-8/h1-4H,5H2
| InChIKey = WNZQDUSMALZDQF-UHFFFAOYAW
| StdInChI = 1S/C8H6O2/c9-8-7-4-2-1-3-6(7)5-10-8/h1-4H,5H2
| StdInChIKey = WNZQDUSMALZDQF-UHFFFAOYSA-N
|Section2={{Chembox Properties
| C=8|H=6|O=2
| Appearance =
| Density =
| MeltingPtC = 75 to 77
| MeltingPt_ref = ^[1]
| BoilingPtC = 290
| BoilingPt_ref = ^[2]
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}

Phthalide is an organic chemical compound with the molecular formula C₈H₆O₂. It is a lactone that serves as the core chemical structure for a variety of more complex chemical compounds including dyes (such as phenolphthalein), fungicides (such as tetrachlorophthalide, often referred to simply as "phthalide"), and natural oils (such as butylphthalide).

Uses

Phthalide is used in the synthesis of several pharmaceutical drugs including isoxepac, vatalanib, and hydralazine as well as the pesticide {{ill|kresoxim-methyl|de|Kresoxim-methyl}}.{{cn|date=February 2018}}

Examples

References

1. ^{{cite journal | author = Kumar, R. Arun | journal = Advanced Synthesis & Catalysis | year = 2011 | volume = 353 | issue = 2+3 | pages = 401–410 | doi = 10.1002/adsc.201000580 | title = Synthesis of 3H-Quinazolin-4-ones and 4H-3,1-Benzoxazin-4-ones via Benzylic Oxidation and Oxidative Dehydrogenation using Potassium Iodide-tert-Butyl Hydroperoxide | last2 = Maheswari | first2 = C. Uma | last3 = Ghantasala | first3 = Satheesh | last4 = Jyothi | first4 = C. | last5 = Reddy | first5 = K. Rajender}}
2. ^{{Cite journal | author = Kus, Nermin Simsek | journal = Asian Journal of Chemistry|title=Some oxidation reactions with molecular oxygen in subcritical water | year = 2008 | volume = 20 | issue = 2 | pages = 1226–1230}}

1 : Phthalides

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