| 词条 | Plasmepsin II |
| 释义 |
| Name = Plasmepsin II | EC_number = 3.4.23.39 | CAS_number = 159447-18-4 | IUBMB_EC_number = 3/4/23/39 | GO_code = | image = PDB 3f9q EBI.png | width = | caption = }}Plasmepsin II ({{EC number|3.4.23.39}}, aspartic hemoglobinase II, PFAPD) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction Hydrolysis of the bonds linking certain hydrophobic residues in hemoglobin or globin. Also cleaves the small molecule substrates such as Ala-Leu-Glu-Arg-Thr-Phe-Phe(NO2)-Ser-Phe-Pro-Thr This enzyme is present in malaria organism, Plasmodium. References1. ^{{cite journal | vauthors = Dame JB, Reddy GR, Yowell CA, Dunn BM, Kay J, Berry C | title = Sequence, expression and modeled structure of an aspartic proteinase from the human malaria parasite Plasmodium falciparum | journal = Molecular and Biochemical Parasitology | volume = 64 | issue = 2 | pages = 177–90 | date = April 1994 | pmid = 7935597 | doi = 10.1016/0166-6851(94)90024-8 }} 2. ^{{cite journal | vauthors = Gluzman IY, Francis SE, Oksman A, Smith CE, Duffin KL, Goldberg DE | title = Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway | journal = The Journal of Clinical Investigation | volume = 93 | issue = 4 | pages = 1602–8 | date = April 1994 | pmid = 8163662 | pmc = 294190 | doi = 10.1172/JCI117140 }} 3. ^{{cite journal | vauthors = Hill J, Tyas L, Phylip LH, Kay J, Dunn BM, Berry C | title = High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum | journal = FEBS Letters | volume = 352 | issue = 2 | pages = 155–8 | date = September 1994 | pmid = 7925966 | doi = 10.1016/0014-5793(94)00940-6 }} External links
1 : EC 3.4.23 |
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