词条 | Sulforidazine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470473917 | IUPAC_name = 102-[(RS)-1-Methylpiperidin-2-yl]ethyl2-(methylsulfonyl)-10H-phenothiazine | image = Sulforidazine.svg | width = 200 | image2 = Sulforidazine3d.png | width2 = 180 | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | metabolism = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 14759-06-9 | ATC_prefix = none | PubChem = 31765 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 29458 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = B7599I244X | C=21 | H=26 | N=2 | O=2 | S=2 | molecular_weight = 402.575 g/mol | smiles = O=S(=O)(c2cc1N(c3c(Sc1cc2)cccc3)CCC4N(C)CCCC4)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C21H26N2O2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)26-21-11-10-17(15-19(21)23)27(2,24)25/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FLGCRGJDQJIJAW-UHFFFAOYSA-N }}Sulforidazine (Imagotan, Psychoson, Inofal) a typical antipsychotic and a metabolite of thioridazine; it and mesoridazine are more potent than the parent compound, whose pharmacological effects are believed by some to be largely due to its metabolism into sulforidazine and mesoridazine.[1] References1. ^{{cite journal|vauthors=Niedzwiecki DM, Mailman RB, Cubeddu LX |title= Greater potency of mesoridazine and sulforidazine compared with the parent compound, thioridazine, on striatal dopamine autoreceptors| journal=Journal of Pharmacology and Experimental Therapeutics|date=March 1984 |volume=228 |issue=3| pages=636–9|pmid=6707914}} {{Antipsychotics}}{{Adrenergics}}{{Cholinergics}}{{Dopaminergics}}{{Histaminergics}}{{Tricyclics}}{{nervous-system-drug-stub}} 5 : Abandoned drugs|Typical antipsychotics|Phenothiazines|Piperidines|Sulfones |
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