词条 | Propazepine |
释义 |
| ImageFile = File:Prazepine.svg | ImageSize = 160px | ImageAlt = | IUPACName =3-(6,11-Dihydrobenzo[c][1]benzazepin-5-yl)-N,N-dimethylpropan-1-amine | OtherNames =Prazepine, Proazepine | Section1 = {{Chembox Identifiers | CASNo = 73-07-4 | PubChem =299322 | ChemSpiderID = 264414 | UNII = 72O4809PU1 | SMILES =CN(C)CCCN1CC2=CC=CC=C2CC3=CC=CC=C31 | Section2 = {{Chembox Properties |H=24 |C=19 |N=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Propazepine is a tricyclic antidepressant (TCA).[1] Propazepine is sometimes confused with imipramine, which has the central ring nitrogen in a different location.[1] Prazepine is the International nonproprietary name of this compound.[2] Prazepine is also reported to be one of the many synonyms of imipramine.[3] Propazepine can be synthesized chemically.[4][5] Propazepine appears to never have actually been used as a tricyclic antidepressant outside of initial medical tests;{{citation needed|date=January 2017}} therefore, there is little information about it. References1. ^1 {{cite journal |doi=10.1007/BF00411159|title=Electrophysiological comparison of the action of imipramine and propazepine|journal=Psychopharmacologia|volume=3|issue=6|pages=423–431| pmid=13967414|year=1962|last1=Benešová|first1=O.|last2=Bohdanecký|first2=Z.|last3=Votava|first3=Z.}} 2. ^{{cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/299322#section=Top|title=Propazepine – C19H24N2|work=Pubchem}} 3. ^{{cite web|url=http://www.chemspider.com/Chemical-Structure.3568.html|title=Imipramine – C19H24N2 |work=ChemSpider}} 4. ^{{cite journal|doi=10.1021/jm00325a016|pmid=14287270|title=Derivatives of Morphanthridine|journal=Journal of Medicinal Chemistry|volume=8|pages=74–80|year=1965|last1=Werner|first1=L. H.| last2=Ricca|first2=S.|last3=Mohacsi|first3=E.|last4=Rossi|first4=A.|last5=Arya|first5=V. P.}} 5. ^{{cite journal|doi=10.1135/cccc19650445|title=Neurotrope und psychotrope substanzen II. Morphanthridin und derivate. Neue synthese des propazepins|journal=Collection of Czechoslovak Chemical Communications|volume=30|issue=2|pages=445–462|year=1965|last1=Jílek|first1=J. O.|last2=Pomykáček|first2=J.|last3=Svátek|first3=E.|last4=Seidlová|first4=V.|last5=Rajšner|first5=M.|last6=Pelz|first6=K.|last7=Hoch|first7=B.|last8=Protiva|first8=M.|trans-title=Neurotropic and psychotropic substances II. Morphanthridin and derivatives. New Synthesis of propazepins|language=Czech}} Further reading
2 : Amines|Tricyclic antidepressants |
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