| 词条 | Prostaglandin G2 |
| 释义 |
| ImageFile = Prostaglandin G2.svg | ImageSize = | IUPACName = (5Z)-7(1R,4S,5R,6R)-6-[(1E,3S)-3-Hydroperoxy-1-octen-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl5-heptenoic acid | OtherNames = | Section1 = {{Chembox Identifiers | CASNo = 51982-36-6 | PubChem = 5280883 | ChemSpiderID = 4444406 | EINECS = 200-662-2 | ChEBI = 27647 | KEGG = C05956 | SMILES = CCCCC[C@@H](/C=C/[C@H]1[C@H]2C[C@@H]([C@@H]1C/C=C\\CCCC(=O)O)OO2)OO | InChI = 1/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | InChIKey = SGUKUZOVHSFKPH-YNNPMVKQBO | StdInChI = 1S/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1 | StdInChIKey = SGUKUZOVHSFKPH-YNNPMVKQSA-N | Section2 = {{Chembox Properties | Formula = C20H32O6 | MolarMass = 368.464 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | Autoignition = }} Prostaglandin G2 is an organic peroxide belonging to the family of prostaglandins.[1] The compound has been isolated as a solid, although it is usually used in vivo. It quickly converts into prostaglandin H2, a process catalyzed by the enzyme COX. Prostaglandin G2 is produced from the fatty acid arachidonic acid. The reaction, an oxygenation, requires the enzyme cyclooxygenase, which inserts two molecules of O2 into the C-H bonds of the substrate acid.[1][2] References1. ^1 {{cite journal|title=The cyclooxygenase reaction mechanism|author1=van der Donk, Wilfred A.|author2= Tsai Ah-Lim|author3=Kulmacz Richard J.|journal=Biochemistry|year=2002|volume=41|pages=15451-8|doi=10.1021/bi026938h}} {{Prostanoid signaling modulators}}{{Nuclear receptor modulators}}{{organic-compound-stub}}2. ^{{cite web|url=https://www.scbt.com/scbt/product/prostaglandin-g2-51982-36-6|title=Prostaglandin G2|publisher=Santa cruz biotechnology, inc|access-date=27 April 2015}} 1 : Prostaglandins |
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