“Prostamide/prostaglandin F2alpha synthase”的意思、由来-开放百科全书

词条

Prostamide/prostaglandin F2alpha synthase

释义

References
External links

| Name = Prostamide/prostaglandin F2alpha synthase
| EC_number = 1.11.1.20
| CAS_number =
| IUBMB_EC_number = 1/11/1/20
| GO_code =
| image =
| width =
| caption =
}}Prostamide/prostaglandin F2alpha synthase ({{EC number|1.11.1.20}}, prostamide/PGF synthase, prostamide F synthase, prostamide/prostaglandin F synthase, tPGF synthase) is an enzyme with systematic name thioredoxin:(5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate oxidoreductase .^[1]^[2] This enzyme catalyses the following chemical reaction

thioredoxin + (5Z,9alpha,11alpha,13E,15S)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate thioredoxin disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dienoate

This enzyme contains a thioredoxin-type disulfide as a catalytic group.

References

1. ^{{cite journal | vauthors = Moriuchi H, Koda N, Okuda-Ashitaka E, Daiyasu H, Ogasawara K, Toh H, Ito S, Woodward DF, Watanabe K | title = Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily | journal = The Journal of Biological Chemistry | volume = 283 | issue = 2 | pages = 792–801 | date = January 2008 | pmid = 18006499 | doi = 10.1074/jbc.M705638200 }}
2. ^{{cite journal | vauthors = Yoshikawa K, Takei S, Hasegawa-Ishii S, Chiba Y, Furukawa A, Kawamura N, Hosokawa M, Woodward DF, Watanabe K, Shimada A | title = Preferential localization of prostamide/prostaglandin F synthase in myelin sheaths of the central nervous system | journal = Brain Research | volume = 1367 | pages = 22–32 | date = January 2011 | pmid = 20950588 | doi = 10.1016/j.brainres.2010.10.019 }}

External links

{{MeshName|Prostamide/prostaglandin+F2alpha+synthase}}

1 : EC 1.11.1

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