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词条 Pseudotropine acyltransferase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Pseudotropine acyltransferase
| EC_number = 2.3.1.186
| CAS_number = 138440-78-5, 162535-26-4
| IUBMB_EC_number = 2/3/1/186
| GO_code =
| image =
| width =
| caption =
}}Pseudotropine acyltransferase ({{EC number|2.3.1.186}}, pseudotropine:acyl-CoA transferase, tigloyl-CoA:pseudotropine acyltransferase, acetyl-CoA:pseudotropine acyltransferase, pseudotropine acetyltransferase, pseudotropine tigloyltransferase, PAT) is an enzyme with systematic name acyl-CoA:pseudotropine O-acyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction

acyl-CoA + pseudotropine CoA + O-acylpseudotropine

This enzyme exhibits absolute specificity for the exo/3beta configuration found in pseudotropine as tropine (tropan-3alpha-ol).

References

1. ^{{cite journal | title = Tigloyl-CoA:pseudotropine acyltransferase — an enzyme of tropane alkaloid biosynthesis | vauthors = Rabot S, Peerless AC, Robins RJ |journal = Phytochemistry |date = 1995 |volume = 39 |pages = 315–322 |pmid = |doi=10.1016/0031-9422(94)00907-b}}
2. ^{{cite journal | vauthors = Robins RJ, Bachmann P, Robinson T, Rhodes MJ, Yamada Y | title = The formation of 3 alpha- and 3 beta-acetoxytropanes by Datura stramonium transformed root cultures involves two acetyl-CoA-dependent acyltransferases | journal = FEBS Letters | volume = 292 | issue = 1-2 | pages = 293–7 | date = November 1991 | pmid = 1959620 | doi = 10.1016/0014-5793(91)80887-9 }}
3. ^{{cite journal | title = Esterification reactions in the biosynthesis of tropane alkaloids in transformed root cultures | vauthors = Robins RJ, Bachmann P, Peerless AC |author4 =Rabot, S. |journal = Plant Cell, Tissue Organ Cult. |date = 1994 |volume = 38 |pages = 241–247 |pmid = |doi=10.1007/bf00033883}}
4. ^{{cite journal | vauthors = Boswell HD, Dräger B, McLauchlan WR, Portsteffen A, Robins DJ, Robins RJ, Walton NJ | title = Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura | journal = Phytochemistry | volume = 52 | issue = 5 | pages = 871–8 | date = November 1999 | pmid = 10626376 | doi = 10.1016/S0031-9422(99)00293-9 }}

External links

  • {{MeshName|Pseudotropine+acyltransferase}}
{{Acyltransferases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 2.3.1

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