词条 | PX-2 |
释义 |
| IUPAC_name = (R)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide | image = PX-2 structure.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = Schedule II | legal_UK = | legal_US = | legal_status = Illegal in China, Singapore, Sweden | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = | ATC_prefix = | ATC_suffix = | PubChem = | ChemSpiderID = 32741702 | smiles = O=C(N[C@@H](C(N)=O)CC1=CC=CC=C1)C2=NN(CCCCCF)C3=C2C=CC=C3 | StdInChI = 1S/C22H25FN4O2/c23-13-7-2-8-14-27-19-12-6-5-11-17(19)20(26-27)22(29)25-18(21(24)28)15-16-9-3-1-4-10-16/h1,3-6,9-12,18H,2,7-8,13-15H2,(H2,24,28)(H,25,29)/t18-/m1/s1 | StdInChIKey = OJTAHWMZBJRSIR-GOSISDBHSA-N | C=22 | H=25 | N=4 | O=2 | F=1 | molecular_weight = 396.47 g/mol }} PX-2 (also known as 5F-APP-PINACA, FU-PX and PPA(N)-2201) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.[1][2] It contains a phenylalanine amino acid amide as part of its structure. LegalitySweden's public health agency suggested classifying PX-2 as hazardous substance on November 10, 2014.[3] PX-2 is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.[4] As of October 2015 PX-2 is a controlled substance in China.[5] See also{{div col|colwidth=30em}}
References1. ^{{cite web | url=https://www.caymanchem.com/app/template/Product.vm/catalog/16434 | title=PX 2 | publisher=Cayman Chemical | accessdate=15 July 2015}} {{Cannabinoids}}{{Cannabinoidergics}}{{cannabinoid-stub}}2. ^{{cite journal | title=Identification and analytical characterization of four synthetic cannabinoids ADB-BICA, NNL-1, NNL-2, and PPA(N)-2201 |author1=Zhenhua Qian |author2=Wei Jia |author3=Tao Li |author4=Zhendong Hua |author5=Cuimei Liu | journal=Drug Testing and Analysis |volume = 9|issue=1 |pages=51–60 | date=2016 | doi=10.1002/dta.1990|pmid=27239006 }} 3. ^{{cite web | url=http://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2014/november/cannabinoider-foreslas-bli-klassade-som-halsofarlig-vara/ | title=Cannabinoider föreslås bli klassade som hälsofarlig vara | publisher=Folkhälsomyndigheten | accessdate=16 July 2015}} 4. ^{{cite web | url=http://www.cnb.gov.sg/Libraries/CNB_Newsroom_Files/CNB_NR_-_30_Apr_2015.sflb.ashx | title=CNB NEWS RELEASE | publisher=Central Narcotics Bureau (CNB) | date=30 April 2015 | accessdate=24 July 2015}} 5. ^{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}} 5 : Indazoles|Cannabinoids|Designer drugs|Indazolecarboxamides|Organofluorides |
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