| 词条 | Pío del Río Hortega |
| 释义 |
| name = Pío del Río Hortega | image = Estatua Pío del Río Hortega Museo Ciencia (Valladolid), detalle.JPG | image_size = | caption = Pío del Río Hortega outside Valladolid Science Museum | birth_name = | birth_date = 5 May 1882 | birth_place = Portillo, Valladolid | death_date = 1 June 1945 (aged 63) | death_place = Buenos Aires | death_cause = Neoplasm | residence = | other_names = | known_for = discovering microglia | education = | employer = | occupation = | title = | salary = | networth = | height = | weight = | term = | predecessor = | successor = | party = | boards = | religion = | spouse = | partner = | children = | parents = | relatives = | signature = | website = | footnotes = | nationality = Spanish }} Pío del Río Hortega (1882 – 1945) was a Spanish neuroscientist who discovered microglia. BiographyRío Hortega was born in Portillo, Valladolid on 5 May 1882.[1] He studied locally and qualified to practice medicine in 1905. He obtained his doctorate at the University of Madrid by researching the pathology of brain tumours. In 1913 he was funded to study research histology in France and Germany but the outbreak of war between them forced him to return to Spain.[1] He worked with the histologist Santiago Ramón y Cajal and briefly with Wilder Penfield. Ramón y Cajal discovered neurons, Penfield helped explain oligodendroglia.[1] whilst Rio Hortega discovered microglia.[2] which are the cells that protect the brain from infection. He managed to identify microglia between 1919 and 1921 by staining the cells with silver carbonate.[2] His method of staining also led to the discovery of oligodendroglia in 1921, which both he and Penfield are now credited with.[1] However it was Rio Hortega who named the cells.[3] His discoveries in 1920 created issues with Ramón y Cajal, who led the lab, as he had earlier won the Nobel prize. By 1931 del Río Hortega was leading Spain's cancer institute, but he left the country when the civil war broke out in 1936.[3] War spreading across Europe found him in Paris at the Pitié-Salpêtrière Hospital before he went to the University of Oxford to work with the British neurosurgeon Hugh Cairns.[4] The bombing of Britain by Germany in World War II drove him on to Argentina. His escape was funded by the Spanish Cultural Institute, who continued to support him as he created his own laboratory in 1942. Río Hortega died in Buenos Aires on 1 June 1945 from a malignant neoplasm.[3] References{{commons category|Pío del Río Hortega}}1. ^1 {{cite journal|last=Gill|first=AS|author2=DK Binder |title=Wilder Penfield, Pío del Río-Hortega, and the discovery of oligodendroglia|journal=Neurosurgery|date=May 2007|volume=60|pages=discussion 940–8.|pmid=17460531|doi=10.1227/01.NEU.0000255448.97730.34|issue=5}} {{Authority control}}{{Use dmy dates|date=March 2017}}{{DEFAULTSORT:Rio Hortega, Pio}}2. ^1 {{cite web|title=Pio del Rio Hortega|url=http://www.britannica.com/EBchecked/topic/1725960/Pio-del-Rio-Hortega|publisher=Encyclopædia Britannica|accessdate=18 December 2012}} 3. ^1 2 3 4 {{cite web|title=Historical perspective on oligodendrocytes and myelin|url=http://tigger.uic.edu/~abouller/history.html|publisher=University of Illinois at Chicago|accessdate=18 December 2012}} 4. ^{{cite web|title=Pio_del_Rio-Hortega (translation)|url=https://translate.google.com/translate?hl=en&sl=es&u=http://www.historiadelamedicina.org/hortega.html&prev=/search%3Fq%3DPio%2Bdel%2BRio-Hortega%26hl%3Den%26client%3Dfirefox-a%26hs%3Dmh4%26tbo%3Dd%26rls%3Dorg.mozilla:en-US:official&sa=X&ei=0cvQUJuBOsiA0AWCx4HQCg&ved=0CHkQ7gEwBw|publisher=historiadelamedicina.org|accessdate=18 December 2012}} 9 : 1882 births|1945 deaths|People from Valladolid|Spanish neuroscientists|University of Valladolid alumni|Histologists|LGBT scientists|LGBT people from Spain|LGBT scientists from Spain |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。