| 词条 | Raphanin | ||||||||||
| 释义 |
| ImageFile = Raphanin.png | ImageSize = 200px | IUPACName = 4-Isothiocyanato-1-(methylsulfinyl)but-1-ene | OtherNames = Sulforaphen; Sulforaphene; Sativin |Section1={{Chembox Identifiers | CASNo = 592-95-0 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem = 6433206 | ChemSpiderID = 16736047 | SMILES = S=C=N/CC\\C=C\\S(=O)C | InChI = 1/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3 | InChIKey = QKGJFQMGPDVOQE-UHFFFAOYAU | StdInChI = 1S/C6H9NOS2/c1-10(8)5-3-2-4-7-6-9/h3,5H,2,4H2,1H3 | StdInChIKey = QKGJFQMGPDVOQE-UHFFFAOYSA-N |Section2={{Chembox Properties | C=6 | H=9 | N=1 | O=1 | S=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage.[1][2] It was first described by G. Ivanovics and S. Horvath in 1947.[3][4] Raphanin inhibits activity of viruses, some fungi and various bacteria including Staphylococcus, Streptococcus, Pneumococcus and Escherichia coli (see table). The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione.[3][5][7][6][7] The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in traditional Chinese medicine.[8] However, in the abstract to his 1947 paper, Ivanovics noted that because raphanin is highly toxic, it did not "hold the promise of a useful therapeutic agent".[9]
See also
References1. ^{{cite book|last1=Sinha|first1=Nirmal K.|last2=Hui|first2=Y. H. |author3=Muhammad Siddiq |author4=Jasim Ahmed|title=Handbook of Vegetables and Vegetable Processing|url=https://books.google.com/books?id=Fz58umYZVK8C&pg=PT156|year=2010|publisher=John Wiley and Sons|isbn=978-0-8138-1541-1|page=156}} 2. ^{{cite journal|doi=10.1007/s00217-007-0674-0|title=Comparison of glucosinolate levels in commercial broccoli and red cabbage from conventional and ecological farming |journal=European Food Research and Technology|author1=Michael Meyer |author2=Sieghard T. Adam |lastauthoramp=yes |volume=226|issue=6|pages=1429–1437}} 3. ^1 {{cite book|last=Baron|first=Abraham Louis|title=Handbook of antibiotics|url=https://books.google.com/books?id=vtbQAAAAMAAJ|year=1950|publisher=Reinhold|page=215}} 4. ^{{Cite journal |author1=Ivãnovics, G. |author2=S. Horvãth |lastauthoramp=yes | title = Raphanin, an Antibacterial Principle of the Radish (Raphanus sativus) | journal = Nature | issue = 4061 | pages = 297–298 |year=1947 | doi = 10.1038/160297a0 |pmid=20261763 | volume=160}} 5. ^{{cite book|last=Florey|first=Howard|title=Antibiotics: a survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants|url=https://books.google.com/books?id=iNXwAAAAMAAJ|year=1949|publisher=Oxford University Press|pages=625–6}} 6. ^{{cite book|title=Acta microbiologica Academiae Scientiarum Hungaricae|url=https://books.google.com/books?id=5TVMAAAAYAAJ|year=1968|publisher=Magyar Tudományos Akadémia|pages=311–3}} 7. ^{{cite book|last=Summers|first=Sean|title=World History on Satan's Diet|url=https://books.google.com/books?id=RkSbK0ujZyIC&pg=PA4|year= 2007|publisher=Wheatmark, Inc.|isbn=978-1-58736-806-6|page=4}} 8. ^{{cite book|last=Hu|first=Shiu-ying|title=Food plants of China|url=https://books.google.com/books?id=2OiYydyrsygC&pg=PA132|year=2005|publisher=Chinese University Press|isbn=978-962-996-229-6|page=132}} 9. ^{{Cite journal |author1=Ivànovics, G. |author2=Horvath, S. |lastauthoramp=yes | title = Isolation and Properties of Raphanin, an Antibacterial Substance from Radish Seed | journal = Experimental Biology and Medicine | volume = 66 | pages = 625–630|pmid=18900045 | year = 1947 | issue=3 | doi=10.3181/00379727-66-16177}} 10. ^1 {{cite book|last1=Chang|first1=Hson-Mou|last2=Pui-Hay|first2=Paul|last3=Yao|first3=Sih-Cheng|title=Pharmacology and Applications of Chinese Material Medical|url=https://books.google.com/books?id=SU_ZX6lI1OIC&pg=PA969|year= 2001|publisher=World Scientific|isbn=978-981-02-3694-6|page=969}} External links
2 : Antibiotics|Isothiocyanates |
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