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词条 Rohon-Beard cell
释义

  1. See also

  2. References

Rohon-Beard cells are specialized neurons with mechanoreceptive properties. They occur during the embryonic stage of development and are found in the dorsal part of the spinal cord in fish and amphibians.[2]

Rohon-Beard neurons develop on the border between the ectoderm epidermal (surface) and neuroectoderm, first in the order of receptor neurons.[3]

In most species Rohon-Beard cells disappear during the course of ontogenetic development (e.g. in zebrafish during the first two to four weeks of development, at the late larval, early juvenile stage to be, replaced by a dorsal root ganglion of spinal nerves)[4] by apoptosis.[5]

John Beard and Joseph Victor Rohon first described these cells, independently of each other.

See also

  • Neural crest

References

1. ^{{Cite journal | last1 = Shimada | first1 = N. | last2 = Sokunbi | first2 = G. | last3 = Moorman | first3 = SJ. | title = Changes in gravitational force affect gene expression in developing organ systems at different developmental times. | journal = BMC Dev Biol | volume = 5 | issue = | pages = 10 | month = | year = 2005 | doi = 10.1186/1471-213X-5-10 | PMID = 15927051 | pmc=1177936}}
2. ^{{Cite book | last1 = Fox | first1 = Harold | title = Amphibian morphogenesi | year = 1984 | publisher = Humana | location = Clifton, N.J. | isbn = 0-89603-043-1 | pages = }}
3. ^{{cite journal | last1 = Rossi | first1 = CC. | last2 = Kaji | first2 = T. | last3 = Artinger | first3 = KB. | title = Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border. | journal = Dev Dyn | volume = 238 | issue = 4 | pages = 931–43 |date=Apr 2009 | doi = 10.1002/dvdy.21915 | PMID = 19301392 | pmc=2755227}}
4. ^{{Cite journal | last1 = Kanungo | first1 = J. | last2 = Zheng | first2 = YL. | last3 = Mishra | first3 = B. | last4 = Pant | first4 = HC. | title = Zebrafish Rohon-Beard neuron development: cdk5 in the midst. | journal = Neurochem Res | volume = 34 | issue = 6 | pages = 1129–37 |date=Jun 2009 | doi = 10.1007/s11064-008-9885-4 | PMID = 19067160 }}
5. ^{{Cite journal | last1 = Reyes | first1 = R. | last2 = Haendel | first2 = M. | last3 = Grant | first3 = D. | last4 = Melancon | first4 = E. | last5 = Eisen | first5 = JS. | title = Slow degeneration of zebrafish Rohon-Beard neurons during programmed cell death. | journal = Dev Dyn | volume = 229 | issue = 1 | pages = 30–41 |date=Jan 2004 | doi = 10.1002/dvdy.10488 | PMID = 14699575 }}
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1 : Neurons

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