“Rubratoxin”的意思、由来-开放百科全书

Rubratoxins are hepatotoxic mycotoxin produced by Penicillium rubrum and Penicillium purpurogenum. Rubratoxin A and rubratoxin B have been known since 1950s, while rubratoxin C was recently reported.^[1] Rubratoxins are also known as protein phosphatase 2A (PP2A) specific inhibitor. The PP2A inhibitory activity of rubratoxin A is about 100-fold higher than rubratoxin B ^[2] and rubratoxin A is now used as a chemical probe for PP2A research.

1. ^{{Cite journal|last = Chen|first = Ri-Dao|last2 = Yan|first2 = Zheng|last3 = Zou|first3 = Jian-Hua|last4 = Wang|first4 = Nan|last5 = Dai|first5 = Jun-Gui|date = 2014-09-01|title = Rubratoxin C, a new nonadride derivative from an endophytic fungus Penicillium sp. F-14|url = http://www.sciencedirect.com/science/article/pii/S1001841714001429|journal = Chinese Chemical Letters|volume = 25|issue = 9|pages = 1308–1310|doi = 10.1016/j.cclet.2014.03.040}}
2. ^{{Cite journal|last = Wada|first = Shun-ichi|last2 = Usami|first2 = Ihomi|last3 = Umezawa|first3 = Yoji|last4 = Inoue|first4 = Hiroyuki|last5 = Ohba|first5 = Shun-ichi|last6 = Someno|first6 = Tetsuya|last7 = Kawada|first7 = Manabu|last8 = Ikeda|first8 = Daishiro|date = 2010-03-01|title = Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis|journal = Cancer Science|volume = 101|issue = 3|pages = 743–750|doi = 10.1111/j.1349-7006.2009.01438.x|issn = 1349-7006|pmid = 20028386}}

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