| 词条 | Temefos |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444215306 | ImageFile=Temefos.svg | ImageFile2=Temefos 3D.png | ImageSize=300px | ImageSize2=300px | IUPACName=O,O,O′,O′-Tetramethyl O,O′-sulfanediylbis(1,4-phenylene) diphosphorothioate | OtherNames=[4-(4-dimethoxyphosphinothioyloxyphenyl)sulfanylphenoxy]- dimethoxy-sulfanylidene-phosphorane |Section1={{Chembox Identifiers | UNII_Ref = {{fdacite|correct|FDA}} | UNII = ONP3ME32DL | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5199 | InChI = 1/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3 | InChIKey = WWJZWCUNLNYYAU-UHFFFAOYAC | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = WWJZWCUNLNYYAU-UHFFFAOYSA-N | CASNo_Ref = {{cascite|correct|??}} | CASNo=3383-96-8 | PubChem=5392 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1355821 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D06062 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 38954 | SMILES = S=P(OC)(OC)Oc2ccc(Sc1ccc(OP(=S)(OC)OC)cc1)cc2 | MeSHName=Temefos |Section2={{Chembox Properties | C=16 | H=20 | O=6 | P=2 | S=3 | Appearance= white, crystalline solid[1] | Density=1.32 g cm−3 | MeltingPtC=30 | BoilingPtC=120-125[1] | BoilingPt_notes = (decomposes) | Solubility= insoluble[1] | VaporPressure = 0.00000007 mmHg (20°C)[1] |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = | PEL = 15 mg/m3[1] | IDLH = N.D.[1] | REL = TWA 10 mg/m3 (total) TWA 5 mg/m3 (resp)[1] }} Temefos or temephos (trade name Abate) is an organophosphate larvicide used to treat water infested with disease-carrying insects[2] including mosquitoes, midges, and black fly larvae. As with other organophosphates, temephos affects the central nervous system through inhibition of cholinesterase. In larvae, this results in death before reaching the adult stage. In the developing world where the vector-borne disease dengue fever is endemic, temephos is widely used and applied by both private and public pest control in areas of standing water where the Aedes aegypti mosquito breeds in order to reduce the population of this disease-carrying insect.[3] Temephos is also used in the Guinea worm eradication program to kill water fleas that carry guinea worm larvae. Resistance to temephos by A. aegypti has been seen in Brazil. The Brazilian Aedes aegypti resistance monitoring program detected temephos resistance in A. aegypti populations from several localities in the country in 1999 (Funasa 2000, Lima et al. 2003). In 1999, mosquitoes from the city of Rio de Janeiro were already resistant to temephos.[4] References1. ^1 2 3 4 5 6 {{PGCH|0589}} 2. ^Abate Product Information 3. ^New York Times article covering its application in Africa 4. ^{{cite journal |vauthors=Lima JB, Da-Cunha MP, Da Silva RC, etal |title=Resistance of Aedes aegypti to organophosphates in several municipalities in the State of Rio de Janeiro and Espírito Santo, Brazil |journal=Am. J. Trop. Med. Hyg. |volume=68 |issue=3 |pages=329–33 |year=2003 |pmid=12685640 |doi=}} External links
Bibliography
4 : Acetylcholinesterase inhibitors|Organophosphate insecticides|Thioethers|Phosphorothioates |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。