| 词条 | Sclerotiorin |
| 释义 |
| ImageFile = Sclerotiorin.svg | ImageSize = 200px | ImageAlt = | IUPACName = | OtherNames = |Section1={{Chembox Identifiers | CASNo = | PubChem = 6436015 | ChemSpiderID = 4940697 | SMILES = CC[C@H](C)/C=C(\\C)/C=C/C1=CC2=C(C(=O)[C@](C(=O)C2=CO1)(C)OC(=O)C)Cl | InChI = 1/C21H23ClO5/c1-6-12(2)9-13(3)7-8-15-10-16-17(11-26-15)19(24)21(5,27-14(4)23)20(25)18(16)22/h7-12H,6H2,1-5H3/b8-7+,13-9+/t12-,21+/m0/s1 | InChIKey = SWJLTKXURNHVHE-UPWXJBBJBP | StdInChI = 1S/C21H23ClO5/c1-6-12(2)9-13(3)7-8-15-10-16-17(11-26-15)19(24)21(5,27-14(4)23)20(25)18(16)22/h7-12H,6H2,1-5H3/b8-7+,13-9+/t12-,21+/m0/s1 | StdInChIKey = SWJLTKXURNHVHE-UPWXJBBJSA-N }} |Section2={{Chembox Properties | C=21 | H=23 | Cl=1 | O=5 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Sclerotiorin is an antimicrobial Penicillium frequentans isolate. Sclerotiorin is an aldose reductase inhibitor (IC50=0.4 μM) as well as a reversible lipoxygenase inhibitor (IC50=4.2 μM).[1][2] Notes1. ^{{cite journal|pmid=16900332|year=2006|last1=Chidananda|first1=C|last2=Rao|first2=LJ|last3=Sattur|first3=AP|title=Sclerotiorin, from Penicillium frequentans, a potent inhibitor of aldose reductase|volume=28|issue=20|pages=1633–6|doi=10.1007/s10529-006-9133-4|journal=Biotechnology Letters}} {{organic-chem-stub}}2. ^{{cite journal| author=Chidananda C, Sattur AP| title=Sclerotiorin, a novel inhibitor of lipoxygenase from Penicillium frequentans. | journal=J Agric Food Chem | year= 2007 | volume= 55 | issue= 8 | pages= 2879–83 | pmid=17385879 | doi=10.1021/jf062032x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17385879 }} 2 : Chloroarenes|Acetate esters |
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