词条 | Secoisolariciresinol dehydrogenase |
释义 |
| Name = Secoisolariciresinol dehydrogenase | EC_number = 1.1.1.331 | CAS_number = | IUBMB_EC_number = 1/1/1/331 | GO_code = | image = | width = | caption = }} Secoisolariciresinol dehydrogenase ({{EC number|1.1.1.331}}) is an enzyme with the systematic name (-)-secoisolariciresinol:NAD+ oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction: (-)-secoisolariciresinol + 2 NAD+ (-)-matairesinol + 2 NADH + 2 H+ This enzyme is isolated from the plants Forsythia intermedia and Podophyllum peltatum. References1. ^{{cite journal | vauthors = Xia ZQ, Costa MA, Pelissier HC, Davin LB, Lewis NG | title = Secoisolariciresinol dehydrogenase purification, cloning, and functional expression. Implications for human health protection | journal = The Journal of Biological Chemistry | volume = 276 | issue = 16 | pages = 12614–23 | date = April 2001 | pmid = 11278426 | doi = 10.1074/jbc.M008622200 }} 2. ^{{cite journal | vauthors = Youn B, Moinuddin SG, Davin LB, Lewis NG, Kang C | title = Crystal structures of apo-form and binary/ternary complexes of Podophyllum secoisolariciresinol dehydrogenase, an enzyme involved in formation of health-protecting and plant defense lignans | journal = The Journal of Biological Chemistry | volume = 280 | issue = 13 | pages = 12917–26 | date = April 2005 | pmid = 15653677 | doi = 10.1074/jbc.M413266200 }} 3. ^{{cite journal | vauthors = Moinuddin SG, Youn B, Bedgar DL, Costa MA, Helms GL, Kang C, Davin LB, Lewis NG | title = Secoisolariciresinol dehydrogenase: mode of catalysis and stereospecificity of hydride transfer in Podophyllum peltatum | journal = Organic & Biomolecular Chemistry | volume = 4 | issue = 5 | pages = 808–16 | date = March 2006 | pmid = 16493463 | doi = 10.1039/b516563f }} External links
1 : EC 1.1.1 |
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