| 释义 |
- Research
- Early life
- List of works Research articles Book chapters
- References
{{Orphan|date=April 2012}}{{Infobox person
| name = Sema Sgaier
| birth_date = {{birth year and age|1975}}
| birth_place = Tripoli, Libya
| occupation = Scientist, Global Health expert, Documentary photographer
| known_for = Program Officer with the Bill and Melinda Gates Foundation
|awards = "Rising Talent by Women's Forum"
}}Sema K. Sgaier is a scientist, global health expert, and documentary photographer. Sgaier’s expertise includes molecular biology, genetics, genomics, neuroscience, epidemiology, disease surveillance, monitoring & evaluation of programs and policy development. ResearchSgaier was the first to fine tune and apply the technique of Genetic Inducible Fate Mapping (GIFM)[1] to understand how the complex 3D cerebellum develops from early-undifferentiated neuronal cells of the anterior hindbrain.[2] With Tim Yu and colleagues, she discovered that mutations in the gene WDR62 causes microcephaly.[3] At the Center for Global Health Research, Sgaier designed and developed the Sample Registration Health Check-Up Survey to study the underlying risk factors of various diseases in India. She has published on the epidemiology of HIV and sexually transmitted diseases. From 2008, Sgaier wa a Program Officer with the Bill & Melinda Gates Foundation. Sgaier manages HIV prevention programs in India and Kenya, and has been engaged in wide-ranging portfolios such as Monitoring & Evaluation and immunization. She has worked closely with the Indian National AIDS Control Program to assist in the design of their program and strengthen their analytic efforts.[4] She has been selected as a “Rising Talent” [5] by the Women’s Forum for the Economy and Society. Early lifeSgaier was born in 1975 in Tripoli, Libya to a Libyan father and Turkish mother. Sgaier studied Molecular Biology and Genetics at Bogazici University (Istanbul, Turkey) where she graduated with her Bachelor of Science in 2005, ranking first of her class. Sgaier later obtained her Masters in Art in Neuroscience from Brown University in 1999 and Masters in Science and Doctorate of Philosophy (PhD) in Cellular and Molecular Biology (Developmental Genetics) in 2005 from New York University. She conducted her Postdoctoral training in Human Genomics in the Lab of Dr. Christopher A. Walsh at Beth Israel Deaconess Medical Center, Harvard Medical School. She is the recipient of New York University, Brown University fellowships and Beth Israel Deaconess Medical Center fellowships.{{Citation needed|date=February 2012}} Sgaier studied Documentary Photography at the International Center of Photography.{{Citation needed|date=February 2012}} List of worksResearch articles- {{cite journal |doi=10.1136/sextrans-2011-050203 |title=HIV, HSV-2 and syphilis among married couples in India: Patterns of discordance and concordance |year=2011 |last1=Arora |first1=P. |last2=Nagelkerke |first2=N. |last3=Sgaier |first3=S. K. |last4=Kumar |first4=R. |last5=Dhingra |first5=N. |last6=Jha |first6=P. |journal=Sexually Transmitted Infections |volume=87 |issue=6 |pages=516–20 |pmid=21865404}}
- {{cite journal |doi=10.1136/sti.2010.043687 |title=Prevalence and correlates of Herpes Simplex Virus-2 and syphilis infections in the general population in India |year=2010 |last1=Sgaier |first1=S. K. |last2=Mony |first2=P. |last3=Jayakumar |first3=S. |last4=McLaughlin |first4=C. |last5=Arora |first5=P. |last6=Kumar |first6=R. |last7=Bhatia |first7=P. |last8=Jha |first8=P. |journal=Sexually Transmitted Infections |volume=87 |issue=2 |pages=94–100 |pmid=21059842}}
- {{cite journal |doi=10.1038/ng.683 |title=Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture |year=2010 |last1=Yu |first1=Timothy W |last2=Mochida |first2=Ganeshwaran H |last3=Tischfield |first3=David J |last4=Sgaier |first4=Sema K |last5=Flores-Sarnat |first5=Laura |last6=Sergi |first6=Consolato M |last7=Topçu |first7=Meral |last8=McDonald |first8=Marie T |last9=Barry |first9=Brenda J |last10=Felie |first10=Jillian M |last11=Sunu |first11=Christine |last12=Dobyns |first12=William B |last13=Folkerth |first13=Rebecca D |last14=Barkovich |first14=A James |last15=Walsh |first15=Christopher A |journal=Nature Genetics |volume=42 |issue=11 |pages=1015–20 |pmid=20890278 |pmc=2969850|display-authors=8 }}
- {{cite journal |doi=10.1242/dev.027045 |title=The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum |year=2010 |last1=Cheng |first1=Y. |last2=Sudarov |first2=A. |last3=Szulc |first3=K. U. |last4=Sgaier |first4=S. K. |last5=Stephen |first5=D. |last6=Turnbull |first6=D. H. |last7=Joyner |first7=A. L. |journal=Development |volume=137 |issue=3 |pages=519–29 |pmid=20081196 |pmc=2858911}}
- {{cite journal |doi=10.1126/science.1149157 |title=PUBLIC HEALTH: Biobanks in Developing Countries: Needs and Feasibility |year=2007 |last1=Sgaier |first1=S. K. |last2=Jha |first2=P. |last3=Mony |first3=P. |last4=Kurpad |first4=A. |last5=Lakshmi |first5=V. |last6=Kumar |first6=R. |last7=Ganguly |first7=N. K. |journal=Science |volume=318 |issue=5853 |pages=1074–5 |pmid=18006727}}
- {{cite journal |doi=10.1371/journal.pone.0001001 |title=Sexual Risk Factors for HIV Infection in Early and Advanced HIV Epidemics in Sub-Saharan Africa: Systematic Overview of 68 Epidemiological Studies |year=2007 |editor1-last=Siegfried |editor1-first=Nandi |last1=Chen |first1=Li |last2=Jha |first2=Prabhat |last3=Stirling |first3=Bridget |last4=Sgaier |first4=Sema K. |last5=Daid |first5=Tina |last6=Kaul |first6=Rupert |last7=Nagelkerke |first7=Nico |journal=PLoS ONE |volume=2 |issue=10 |pages=e1001 |pmid=17912340 |author8=International Studies of HIV/AIDS (ISHA) Investigators |pmc=1994584}} {{open access}}
- {{cite journal |doi=10.1242/dev.000620 |title=Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins |year=2007 |last1=Sgaier |first1=S. K. |last2=Lao |first2=Z. |last3=Villanueva |first3=M. P. |last4=Berenshteyn |first4=F. |last5=Stephen |first5=D. |last6=Turnbull |first6=R. K. |last7=Joyner |first7=A. L. |journal=Development |volume=134 |issue=12 |pages=2325–35 |pmid=17537797 |pmc=2840613}}
- {{cite journal |doi=10.1186/1471-2458-6-199 |year=2006 |last1=Nagelkerke |first1=Nico JD |last2=Bernsen |first2=Roos MD |last3=Sgaier |first3=Sema |last4=Jha |first4=Prabhat |journal=BMC Public Health |volume=6 |pages=199 |pmid=16884541 |title=Body mass index, sexual behaviour, and sexually transmitted infections: An analysis using the NHANES 1999-2000 data |pmc=1559603}} {{open access}}
- {{cite journal |doi=10.1016/j.ydbio.2006.04.449 |title=Β-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse |year=2006 |last1=Atit |first1=Radhika |last2=Sgaier |first2=Sema K. |last3=Mohamed |first3=Othman A. |last4=Taketo |first4=Makoto M. |last5=Dufort |first5=Daniel |last6=Joyner |first6=Alexandra L. |last7=Niswander |first7=Lee |last8=Conlon |first8=Ronald A. |journal=Developmental Biology |volume=296 |pages=164–76 |pmid=16730693 |issue=1}}
- {{cite journal |doi=10.1016/j.neuron.2004.12.021 |title=Morphogenetic and Cellular Movements that Shape the Mouse Cerebellum |year=2005 |last1=Sgaier |first1=Sema K. |last2=Millet |first2=Sandrine |last3=Villanueva |first3=Melissa P. |last4=Berenshteyn |first4=Frada |last5=Song |first5=Christian |last6=Joyner |first6=Alexandra L. |journal=Neuron |volume=45 |pages=27–40 |pmid=15629700 |issue=1}}
Book chapters- Ramakrishnan, A., Sgaier, S.K., Alexander, A. Scaling HIV Prevention through Partnerships – The Avahan Experience in India. [https://www.amazon.com/Innovative-Health-Partnerships-Diplomacy-Diversity/dp/9814366145/ref=sr_1_1?s=books&ie=UTF8&qid=1327253763&sr=1-1 Innovative Health Partnerships- The Diplomacy of Diversity]. World Scientific Pub Co Inc, 2011.
- Sgaier, S.K. Berenshteyn, F., Joyner, A.L., Miller, S., Song, C. Villanueva, M.P. The Concept of Fate Through the Lens of Genetics, in Beesley, P., S. Hirosue, J. Ruxton, M. Tränkle, C. Turner Eds. [https://www.amazon.com/Responsive-Architectures-Technologies-Philip-Beesley/dp/0978097807 Responsive Architectures: Subtle Technologies]. Riverside Architectural Press, Cambridge, 2006 pp. 26–29
References1. ^{{cite journal |doi=10.1002/dvdy.20884 |title=Genetic inducible fate mapping in mouse: Establishing genetic lineages and defining genetic neuroanatomy in the nervous system |year=2006 |last1=Joyner |first1=Alexandra L. |last2=Zervas |first2=Mark |journal=Developmental Dynamics |volume=235 |issue=9 |pages=2376–85 |pmid=16871622}}
2. ^{{cite journal |doi=10.1016/j.neuron.2004.12.021 |title=Morphogenetic and Cellular Movements that Shape the Mouse Cerebellum |year=2005 |last1=Sgaier |first1=Sema K. |last2=Millet |first2=Sandrine |last3=Villanueva |first3=Melissa P. |last4=Berenshteyn |first4=Frada |last5=Song |first5=Christian |last6=Joyner |first6=Alexandra L. |journal=Neuron |volume=45 |pages=27–40 |pmid=15629700 |issue=1}}{{Primary source inline|date=February 2012}}
3. ^{{cite journal |doi=10.1038/ng.683 |title=Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture |year=2010 |last1=Yu |first1=Timothy W |last2=Mochida |first2=Ganeshwaran H |last3=Tischfield |first3=David J |last4=Sgaier |first4=Sema K |last5=Flores-Sarnat |first5=Laura |last6=Sergi |first6=Consolato M |last7=Topçu |first7=Meral |last8=McDonald |first8=Marie T |last9=Barry |first9=Brenda J |last10=Felie |first10=Jillian M |last11=Sunu |first11=Christine |last12=Dobyns |first12=William B |last13=Folkerth |first13=Rebecca D |last14=Barkovich |first14=A James |last15=Walsh |first15=Christopher A |journal=Nature Genetics |volume=42 |issue=11 |pages=1015–20 |pmid=20890278 |pmc=2969850|display-authors=8 }}{{Primary source inline|date=February 2012}}
4. ^{{Cite web|url=http://www.iasociety.org/Default.aspx?pageId=54&elementId=13906|title=Home|website=www.iasociety.org|language=en-US|access-date=2017-11-16}}
5. ^{{Cite web|url=http://www.womens-forum.com/news/category/posts/2008-international-chinese-nominees|title=Titre de la page|last=www.castoretpollux.com|website=www.womens-forum.com|language=en-EN|access-date=2017-11-16}}
{{authority control}}{{DEFAULTSORT:Sgaier, Sema}} 10 : Boğaziçi University alumni|1975 births|People from Tripoli|Molecular biologists|Brown University alumni|New York University alumni|Harvard Medical School alumni|Women photographers|Living people|Libyan scientists |