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词条 Silence Therapeutics
释义

  1. Profile

     History  Partnerships 

  2. References

  3. External links

{{Infobox company |
| name = Silence Therapeutics PLC
| logo = Silence_Therapeutics_logo.png
| type = Public ({{LSE|SLN}})
| foundation = 1994
| industry = Pharmaceuticals
| num_employees = 50
| homepage = www.silence-therapeutics.com
}}

Silence Therapeutics (AIM:SLN[1]) is a biotechnology company that develops gene therapeutic technology based on RNA interference (RNAi). They are involved in developmental research of targeted RNAi therapeutics for the treatment of serious diseases. Formed in 1994 as a publicly traded drug research and development company, Silence Therapeutics has offices in London and Berlin, with its corporate headquarters at 1 Lyric Square, London.

Profile

The targeting, delivery and ongoing structural modification of sequences are the three platforms for Silence Therapeutics's RNAi therapeutic development. These three platforms are:

  • proprietary siRNA sequences complied using bioinformatics algorithms and scientific research conjugated with GalNac Technology
  • development of siRNA structural features

Silence Therapeutics develops these structural modifications using three exclusive licences from the University of Massachusetts Amherst.

History

In 2005, the company acquired Atugen AG based in Germany, changing the company name to Silence Therapeutics AG. More recently in January 2010, Silence Therapeutics merged with Intradigm Corporation, a privately held biotechnology company in the United States that developed systematic RNA interference.[2]

Partnerships

Silence Therapeutics has multiple partnerships with other pharmaceutical companies, such as AstraZeneca, Pfizer/Quark Pharma and Dainippon Sumitomo.[3]

References

1. ^{{cite web|title=Google Finance Stock Exchange listing for Silence Therapeutics|url=https://www.google.com/finance?q=LON:SLN|accessdate=2011-09-16}}
2. ^{{cite web|first=Stockopedia|url=http://www.stockopedia.co.uk/share-prices/silence-therapeutics-LON:SLN/ |title = Stockopedia - Silence Therapeutics Company History|accessdate=2011-09-16|publisher=Stockopedia}}
3. ^{{cite web|first=Silence Therapeutics|url=http://www.silence-therapeutics.com/content/collaborations/partnerships.htm |title = Silence Therapeutics Collaborative Partnerships|accessdate=2011-09-26|publisher=Silence Therapeutics}}

External links

  • Official website
  • [https://www.wsj.com/articles/SB121187852128322413?mod=us_business_whats_news Wall Street Journal on Alnylam's May 2008 alliance with Takeda Pharmaceutical]
{{Pharmaceutical and biotechnology industry in the United Kingdom}}{{Pharmaceutical companies of the United States}}

5 : Pharmaceutical companies of England|Medical and health organisations based in England|Companies based in the London Borough of Hammersmith and Fulham|1994 establishments in England|Pharmaceutical companies established in 1994

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